Pyrroles
Apexbio Technology LLC Almotriptan Malate 181183-52-8 100mg
Almotriptan Malate (CAS 181183-52-8) is a small molecule belonging to the triptan class acting as a selective agonist at 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptors By stimulating these receptors Almotriptan modulates cranial vasoconstriction and inhibits the release of pro-inflammatory neuropeptides biologically counteracting migraine pathophysiology In research applications Almotriptan Malate is utilized to investigate serotonergic signaling pathways migraine mechanisms and the pharmacodynamics of 5-HT1B/1D receptor modulation in neurological models
Medchemexpress LLC N-Desethyl Sunitinib | 356068-97-8 | 99.9% | 370.42 | 100 MG
N-Desethyl Sunitinib (SU-12662) is a metabolite of Sunitinib. It serves as a good transport substrate for human ABCB1, ABCG2, and murine ABCG2. It is for research use only.
- Good transport substrate for human ABCB1, ABCG2, and murine ABCG2.
- Effective against K562 cells.
- Provided as a solid.
Medchemexpress LLC Sunitinib impurity 28 | 1186651-51-3 | 98.5% | 299.31 | 100 MG
Sunitinib impurity 28 is a chemical substance intended for research use only and is not suitable for human or therapeutic use. It has a CAS Number of 1186651-51-3 and a molecular weight of 299.31.
- High purity of 98.50%
- Reliable product for research purposes
- Available in 100 MG quantity
Medchemexpress LLC Massoia lactone | 54814-64-1 | 25 G
Massoia lactone is a coconut and creamy fragrant compound primarily isolated from Cryptocarya massoy. It is also known as a fragrant biosurfactant produced by the fungus Aureobasidium pullulans.
- Coconut and creamy fragrant compound
- Primarily isolated from Cryptocarya massoy
- Functions as a fragrant biosurfactant
- Produced by Aureobasidium pullulans
- Molecular weight: 168.23
- Chemical formula: C10H16O2
- Appearance: Liquid
- Color: Light yellow to light brown
- Purity: 98.75%
- Storage (pure form): -20°C for 3 years
=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | 1g | 887266109](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471133.jpg-250.jpg)
eMolecules 341031-54-7 | Sunitinib malate | Chemodex Ltd. | MFCD08282795 | 532.569 | C26H33FN4O7 | 98.000 | O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | 1g | 887266109
Sunitinib malate | Chemodex Ltd. | 341031-54-7 | MFCD08282795 | 532.569 | C26H33FN4O7 | 98.000 | O[C@@H](CC(O)=O)C(O)=O.CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C | 1g | 887266109
TARGETMOL CHEMICALS INC Atorvastatin lactone 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Purity 98.16%
Selleck Chemical LLC Sacubitril hemicalcium salt S4426-25mg
Sacubitril (AHU-377) hemicalcium salt a component of the heart failure medicine LCZ696 is a potent inhibitor of neprilysin (neutral endopeptidase NEP)
Medchemexpress LLC HY-13781 500mg Medchemexpress, Pemetrexed (disodium hemipenta hydrate) Pemetrexed sodium hydrate CAS:357166-30-4 Purity:98%
Medchemexpress,HY-13781 500mg Pemetrexed (disodium hemipenta hydrate) Pemetrexed sodium hydrate CAS:357166-30-4 Formula:C20H21N5O6 . 5/2 H2O . 2Na Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Bromoenol lactone-E1878-5MG
Bromoenol lactone((6E)-Bromoenol lactone) is a selective irreversible potent inhibitor of calcium-independent phospholipase A2 (iPLA2 ) with an IC50 value of 7 M It prevents antigen-stimulated exocytosis in mast cells without hindering Ca2 influx
Medchemexpress LLC HY-15816A 5mg Medchemexpress, Ulixertinib (hydrochloride) CAS:1956366-10-1 Purity:>98%
Medchemexpress, HY-15816A 5mg Ulixertinib (hydrochloride) CAS:1956366-10-1 Ulixertinib hydrochloride is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC (6E)-3-bromo-4-(4-phenyl-1,2,3,4-tetrahydronaphthalen-1-ylidene)furan-2(5H)-one | 88070-98-8 | MFCD00270871 | 99.6% | 317.18 g/mol | C16H13BrO2 | 100 MG
Bromoenol lactone is an irreversible, suicide-based inhibitor of phospholipase A2 used as a research reagent to study lipid signaling, inflammation, and enzyme function. It is supplied as a white-to-yellow solid of high purity and is typically prepared in DMSO for in vitro and in vivo experiments. Powder storage at -20°C is recommended; solutions have limited stability.
- Irreversible, suicide-based inhibitor of phospholipase A2.
- High purity suitable for biochemical and pharmacological assays (≈99.6%).
- Molecular weight 317.18 g/mol; chemical formula C16H13BrO2.
- Soluble in DMSO (≈50 mg/mL); sonication recommended for dissolution.
- Powder stability at -20°C for up to 3 years; limited in-solution shelf life.
- Supplied as a solid to allow flexible formulation for in vitro and in vivo use.
Apexbio Technology LLC AHU-377 hemicalcium salt 1369773-39-6 100mg
AHU-377 hemicalcium salt (CAS 1369773-39-6) is a hemicalcium salt form of AHU-377 a potent inhibitor of neprilysin (neutral endopeptidase) with an IC50 of 5 nM As a prodrug AHU-377 is enzymatically converted to its active metabolite LBQ657 following ester cleavage AHU-377 is a key component of LCZ696 co-formulated with valsartan at a 1 1 molar ratio functioning as an angiotensin receptor neprilysin inhibitor (ARNI) In vivo studies demonstrate that oral administration of AHU-377 induces dose-dependent blood pressure reduction in DAHI-SS rats though it has less pronounced effects in DOCA-salt hypertensive models AHU-377 is widely studied in cardiovascular research particularly in the context of heart failure and hypertension