Quinolines and derivatives
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Filtered Search Results
Ambeed 7Bromo1 2dihydroisoquinolin3 4
7-Bromo-1,2-dihydroisoquinolin-3(4H)-one, 943751-93-7, 95%
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Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | 98.0% | 560.59 g/mol | C31H32N2O8 | 1 ML
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine is a protected 2'-O-methyluridine nucleoside used as a building block in oligonucleotide synthesis and nucleoside chemistry. It is supplied as a light yellow solid and as a 10 mM solution in DMSO for laboratory research applications.
- Protected 2'-O-methyl uridine analog for oligonucleotide synthesis.
- Available as a light yellow solid and as a 10 mM solution in DMSO.
- Purity 98.0% (data sheet).
- Molecular formula C31H32N2O8; molecular weight 560.59 g/mol.
- Supplied in multiple solid sizes for scale flexibility.
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TARGETMOL CHEMICALS INC AMG9810 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1 respectively). purity: 98%
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Ambeed 3Chloro5nitrobenzoic acid
3-Chloro-5-nitrobenzoic acid, 34662-36-7, 98%
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 25 MG
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Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor used in research to block proteolytic shedding of cell-surface molecules such as L-selectin and TNF-α. It demonstrates sub-micromolar to low-micromolar activity in human and mouse immune cells and is supplied as a high-purity solid for laboratory experiments.
- Potent inhibition of L-selectin shedding in immune cells.
- Active against TNF-α shedding in monocytes.
- High purity suitable for biochemical and cellular assays.
- Available in multiple pack sizes including small-milligram quantities.
- Provided with datasheet, SDS, and COA for quality traceability.
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Medchemexpress LLC 7-Hydroxycarbostyril | 70500-72-0 | 99.1% | 161.16 | 10 G
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7-Hydroxycarbostyril (synonyms: 7-Hydroxyquinolinone; 2,7-Dihydroxyquinoline) is a quinolinone derivative. It can be used for the synthesis of Brexpiprazole, an orally active antipsychotic agent that acts as a partial agonist of human 5-HT1A and dopamine D2L receptors. This product is for research use only and not sold to patients.
- Quinolinone derivative
- Used for synthesis of Brexpiprazole
- Brexpiprazole acts as a partial agonist of human 5-HT1A and dopamine D2L receptors
- For research use only
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Medchemexpress LLC 1,7-Heptanediamine | 646-19-5 | 98.54% | 130.23 | 10 G
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1,7-Heptanediamine (C7) is a deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM. It appears as a solid below 26°C and a liquid above 29°C, with a colorless to off-white appearance. It is soluble in water at ≥ 100 mg/mL (767.87 mM).
- Deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM
- Appears as a solid below 26°C and a liquid above 29°C
- Colorless to off-white appearance
- Soluble in water at ≥ 100 mg/mL
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 50 MG
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Ro 31-9790 is a synthetic matrix metalloproteinase (MMP) inhibitor used as a research reagent to probe MMP activity, protease-mediated ectodomain shedding, and related cellular pathways. It is supplied as a high-purity solid for laboratory studies and includes handling and storage recommendations to preserve stability.
- High purity, suitable for biochemical and cellular assays.
- Molecular weight 315.41 g/mol and formula C15H29N3O4 for compound identification.
- Off-white to light yellow solid appearance for easy visual confirmation.
- Recommended storage at 4°C; protect from light and store under inert gas; in solvent, store at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO with supplier-provided concentration guidance for assay preparation.
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Ambeed 1R 2S 1Amino2 3dihydro1Hinden
(1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol, 136030-00-7, 98%
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Medchemexpress LLC Recombinant mouse interleukin-31 | >85.0% | 2 UG
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Recombinant mouse interleukin-31 produced in HEK293 cells and supplied as a filtered PBS solution for research applications. The protein is provided as a solution (2 μg vial) with a C-terminal His tag and is characterized by predicted mass and receptor-binding activity suitable for in vitro assays.
- Expressed in HEK293 mammalian cells for native folding and glycosylation.
- C-terminal His tag facilitates purification and detection.
- Predicted molecular mass approximately 17.1 kDa.
- Purity greater than 85% as determined by reducing SDS-PAGE.
- Demonstrated receptor binding activity (ED50 reported in functional assay).
- Supplied in PBS, pH 7.4; store at -80°C and avoid repeated freeze-thaw cycles.
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Ambeed 7Bromo1 2dihydroisoquinolin3 4
7-Bromo-1,2-dihydroisoquinolin-3(4H)-one, 943751-93-7, 95%
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Medchemexpress LLC BSJ-03-204 | 2349356-09-6 | 99.8% | 832.90 | 25 MG
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BSJ-03-204 is a PROTAC that connects ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1. This compound does not induce IKZF1/3 degradation and exhibits anti-cancer activity.
- Potent and selective CDK4/6 dual degrader
- Does not cause IKZF1/3 degradation
- Demonstrates anti-cancer activity
- Potent anti-proliferative effects on MCL cell lines
- Induces G1 arrest
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Medchemexpress LLC BSJ-03-204 | 2349356-09-6 | 99.8% | 832.90 | 1 MG
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BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1. BSJ-03-204 does not induce IKZF1/3 degradation and exhibits anti-cancer activity.
- Potent anti-proliferative effects on MCL cell lines.
- Potently induces a G1 arrest.
- Selectively degrades CDK4/6 in WT cells, not IKZF1/3.
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Medchemexpress LLC Mal-amido-PEG12-acid | 2378428-27-2 | C34H60N2O17 | 50 MG
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Mal-amido-PEG12-acid is a PEG-based PROTAC linker suitable for synthesizing PROTACs. It functions by connecting two distinct ligands, one targeting an E3 ubiquitin ligase and the other for the specific target protein, allowing for the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Can be used in the synthesis of PROTACs.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
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TARGETMOL CHEMICALS INC NOTHOFAGIN 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Nothofagin has antioxidant and antithrombotic activities it possesses anti-inflammatory activity by inhibiting hyperpermeability expression of CAMs and adhesion and migration of leukocytes thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. purity: 99%
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