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Filtered Search Results
Selleck Chemical LLC Bemnifosbuvir Hemisulfate-5MG
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Bemnifosbuvir Hemisulfate (AT-527 RG-6422 RO 7496998) is a hemi-sulfate salt of AT-511 AT-511 is a potent inhibitor of SARS-CoV-2 with an EC90 of 0 47 M
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Selleck Chemical LLC Proflavine Hemisulfate S4236-50mg
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Proflavine Hemisulfate is a topical antiseptic by interchelating DNA thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands
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FUJIFILM BIOSCIENCES INC 5-(CHLOROMETHYL)-8-QUINOLINOL
*Orders for this supplier are non-cancellable/non-returnable once they are processed.* 5-(Chloromethyl)-8-quinolinol Hydrochloride 1GR
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eMolecules 70585-55-6 | 6-HYDROXYQUINOLINE-8-CARBOXYLICACID | MFCD12024807 | 0.25g
AstaTech | 6-HYDROXYQUINOLINE-8-CARBOXYLICACID | 0.25g | 449771839 | K10277 | 95.000 | 70585-55-6 | MFCD12024807 | 189.170 | C10H7NO3
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eMolecules Building Block Tool<|a>
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eMolecules 1137826-05-1 | 6-HYDROXYQUINOLINE-3-CARBOXYLIC ACID | AstaTech | MFCD18417138 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cnc2ccc(O)cc2c1 | 0.25g | 410712917
6-HYDROXYQUINOLINE-3-CARBOXYLIC ACID | AstaTech | 1137826-05-1 | MFCD18417138 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cnc2ccc(O)cc2c1 | 0.25g | 410712917
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Medchemexpress LLC Ethidium bromide | 1239-45-8 | MFCD00011724 | 99.4% | 100 MG
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EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. It is for research use only and not sold to patients. It binds to DNA, allowing visualization under ultraviolet (UV) light.
- Serves as a fluorescent tag (nucleic acid stain)
- Used in molecular biology laboratories for techniques such as agarose gel electrophoresis
- Binds to DNA
- Allows visualization under ultraviolet (UV) light
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Cayman Chemical PropIdIum IodIde 50mg
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A fluorescent probe commonly used to identify dead cells; excitation at 488-535 nm and emission maximum of 617 nm
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Selleck Chemical LLC Dihydroethidium
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Dihydroethidium (DHE HE Hydroethidine PD-MY 003) is a cell-permeable blue fluorogenic probe used for detecting intracellular superoxide radical anion
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Apexbio Technology LLC Dihydroethidium(Synonyms: Hydroethidine, DHE, HE, Dihydroethidine, Ethidium hydride), 5mg, CAS: 104821-25-2.
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Dihydroethidium (CAS 104821-25-2) also known as hydroethidine is a cell-permeable fluorescent probe widely utilized for detecting superoxide anions (O ) in live cells After entering cells dihydroethidium is oxidized by intracellular superoxide anions to ethidium which subsequently intercalates into DNA emitting detectable red fluorescence (excitation/emission 518/605 nm) Unoxidized dihydroethidium exhibits blue fluorescence (355/420 nm) The intensity of the red fluorescence correlates directly with intracellular O concentration Thus dihydroethidium serves as a valuable tool in evaluating oxidative stress and studying associated physiological/pathological processes including apoptosis cell proliferation cardiovascular pathologies diabetes and cancer
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Apexbio Technology LLC Dihydroethidium(Synonyms: Hydroethidine, DHE, HE, Dihydroethidine, Ethidium hydride), 10mg, CAS: 104821-25-2.
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Dihydroethidium (CAS 104821-25-2) also known as hydroethidine is a cell-permeable fluorescent probe widely utilized for detecting superoxide anions (O ) in live cells After entering cells dihydroethidium is oxidized by intracellular superoxide anions to ethidium which subsequently intercalates into DNA emitting detectable red fluorescence (excitation/emission 518/605 nm) Unoxidized dihydroethidium exhibits blue fluorescence (355/420 nm) The intensity of the red fluorescence correlates directly with intracellular O concentration Thus dihydroethidium serves as a valuable tool in evaluating oxidative stress and studying associated physiological/pathological processes including apoptosis cell proliferation cardiovascular pathologies diabetes and cancer
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Apexbio Technology LLC Chelerythrine Chloride 3895-92-9 5mg
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Chelerythrine Chloride (CAS 3895-92-9) is a benzophenanthridine alkaloid widely utilized as a selective antagonist of protein kinase C (PKC) with an IC50 of 0 66 M It acts as a high-specificity inhibitor by targeting the kinase regulatory domain serving as a competitive inhibitor with respect to phosphate receptors and a non-competitive inhibitor toward ATP Chelerythrine also inhibits Bcl-xL inducing apoptosis in mouse embryonic fibroblasts (MEFs) with an IC50 of 1 1 M It activates the JNK1 and p38 pathways via MEKK1 and MKK4 contributing to its pro-apoptotic effects In cellular assays chelerythrine reduces cell viability (MTT IC50 2 6 M) and in animal studies promotes apoptosis through reactive oxygen species generation Its applications extend to research on kinase activity apoptosis antimicrobial activity and anti-inflammatory processes
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Medchemexpress LLC Dihydroethidium | 104821-25-2 | 98.8% | 100 MG
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Dihydroethidium, also known as DHE, is a peroxide indicator that penetrates cell membranes to form a fluorescent protein complex. After entering cells, it localizes mainly in the cell membrane, cytoplasm, and nucleus. It produces inherent blue fluorescence (maximum excitation 370 nm, maximum emission 420 nm) and, after dehydrogenation, combines with RNA or DNA to produce red fluorescence (maximum excitation 300 nm or 535 nm, maximum emission 610 nm).
- Peroxide indicator
- Cell membrane permeable
- Localizes in cell membrane, cytoplasm, and nucleus
- Produces blue fluorescence (Ex: 370 nm, Em: 420 nm)
- Produces red fluorescence after dehydrogenation and binding to RNA/DNA (Ex: 300 nm or 535 nm, Em: 610 nm)
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Medchemexpress LLC Dimidium bromide | 518-67-2 | 98.6% | 250 MG
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Dimidium bromide is a biochemical reagent that can be used as a biological material or organic compound for various life science-related research applications.
- For research use only
- Stable under recommended storage conditions
- Store sealed, away from moisture and light
- Soluble in DMSO at 125 mg/mL
- Shipped at room temperature in continental US
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AdipoGen Ethidium bromide Solution
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Chemical. CAS 1239-45-8. Formula C21H20BrN3. MW 394.31. Synthetic. Ethidium bromide EtBr is the most commonly used nucleic acid stain for PAGE or agarose gel electrophoresis. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA and 25-fold on binding double-stranded DNA so that destaining the background is not necessary with a low stain concentration 10 µg/ml. Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids. Ethidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It confers a deep red stain to DNA by acting as an intercalating agent between the starch bases. It has been shown to bind to single-stranded DNA although not as strongly and triple-stranded DNA. Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. It can be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.
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AdipoGen Propidium Iodide Solution
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Chemical. CAS 25535-16-4. Formula C27H34I2N4. MW 668.39. Synthetic. Most common red-fluorescent nuclear stain. Membrane impermeant and generally excluded from viable cells. It can easily penetrate dead or damaged cells and as such is commonly used for identifying cell viability in a population or as a counterstain in multicolor fluorescent techniques. It binds to DNA and RNA by intercalating between the bases. Suitable for use in fluorescence microscopy, confocal laser scanning microscopy, flow cytometry and fluorometry. Spectral data lambdaex=488-535nm, lambdaem=617nm.
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