Quinolines and derivatives
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Filtered Search Results
Ambeed 3Aminopiperidine2 6dione
3-Aminopiperidine-2,6-dione, 2353-44-8, 98%
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Ambeed 3 4Chlorophenyl N pyridin4ylme
3-(4-Chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide, 915385-81-8, 98%
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Cambridge Isotope Laboratories 1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 3 4 6 7-HexaCN (PCN-66) (unlabeled) 100 ug/mL in nonane 1 mL
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Medchemexpress LLC (1E)-CFI-400437 dihydrochloride | 1247000-76-5 | 98.0% | 565.49 | 5 MG
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(1E)-CFI-400437 dihydrochloride is a potent PLK4 inhibitor with high selectivity. It also inhibits Aurora A, Aurora B, KDR, and FLT-3, demonstrating antiproliferative activity. This compound has shown effectiveness in a mouse xenograft model of tumor growth.
- Potent PLK4 inhibitor with IC50 of 0.6 nM
- Selective against other PLK family members
- Inhibits Aurora A, Aurora B, KDR, and FLT-3
- Exhibits antiproliferative activity
- Effective in mouse xenograft models of tumor growth
- Plasma protein binding is 99%
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Medchemexpress LLC Amino-PEG12-amine | 361543-12-6 | HY-133327 | 99.9% | 588.73 | 250 MG
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Amino-PEG12-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules with two different ligands connected by a linker: one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Enables synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Appears as a colorless to off-white solid-liquid mixture
- Has a purity of 99.92%
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Medchemexpress LLC Azido-PEG12-amine | 2803478-25-1 | 98.0% | 614.73 g/mol | C26H54N4O12 | 50 MG
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Azido-PEG12-amine is a PEG12 linker with an azide group at one terminus and a primary amine at the other, designed for bioconjugation and click chemistry applications.
- Azide functionality enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Primary amine enables conjugation to activated carboxylates such as NHS esters.
- Molecular weight approximately 614.73 g/mol; formula C26H54N4O12.
- High purity by NMR (typically 98.0%).
- Water-soluble PEG12 linker suitable for linker synthesis, PROTACs, and ADCs.
- Store sealed at 4°C, protect from moisture and light.
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Ambeed S 2 9HFluoren9yl methoxy c
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2,3-dimethylbutanoic acid, 169566-81-8, 95%
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Ambeed R tertButyl 3 hydroxymethyl p
(R)-tert-Butyl 3-(hydroxymethyl)piperazine-1-carboxylate, 278788-66-2, 95%
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | MFCD00036665 | 99.9% | 295.18 | 25 MG
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L-Cystathionine dihydrochloride is an analytical standard intended for research and analytical applications. This nonprotein thioether is a key amino acid associated with the metabolic state of sulfur-containing amino acids. It protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs) and plays an important role in cardiovascular protection.
- Analytical standard grade for research and analytical applications.
- Nonprotein thioether and key amino acid.
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs).
- Plays an important role in cardiovascular protection.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Medchemexpress LLC L-Cystathionine (dihydrochloride) | 61125-50-6 | 99.9% | 295.18 | 1 MG
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L-Cystathionine dihydrochloride is a nonprotein thioether and a key amino acid involved in the metabolic state of sulfur-containing amino acids. This white to off-white solid substance is recommended for storage at -20°C in sealed conditions, away from light and moisture, and under nitrogen.
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells
- Significant in cardiovascular protection
- Provided as a white to off-white solid
- Store at -20°C in sealed conditions, away from light and moisture, and under nitrogen
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Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | 295.18 | 5 MG
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L-Cystathionine dihydrochloride is a nonprotein thioether and a key amino acid involved in the metabolic state of sulfur-containing amino acids. It has been shown to protect against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). This suggests an important role for L-Cystathionine in cardiovascular protection.
- Key amino acid associated with the metabolic state of sulfur-containing amino acids
- Protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs)
- Plays an important role in cardiovascular protection
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Cayman Chemical 8 9DiHETE Fatty Acids and Deri
A major metabolite of EPA; produced in liver microsomes by CYP450 monooxygenases
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Medchemexpress LLC 6,8-Diprenylorobol | 66777-70-6 | 1 MG
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6,8-Diprenylorobol is a prenylated isoflavone isolated from the leaves of *Cudrania tricuspidata*. It exhibits an antiproliferative effect and induces apoptosis by activating p53 and generating reactive oxygen species (ROS). It has shown to inhibit proliferation in LoVo and HCT15 cells in a dose- and time-dependent manner and also regulates MAPKs.
- Exhibits antiproliferative effect
- Induces apoptosis by activating p53
- Generates reactive oxygen species (ROS)
- Inhibits proliferation in LoVo and HCT15 cells
- Regulates MAPKs in LoVo and HCT15 cells
- Increases ROS levels in LoVo and HCT15 cells
- Inhibits LPS-induced nitric oxide production in RAW264.7 cells
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Ambeed Methyl 1bromocyclopropanecarbo
Methyl 1-bromocyclopropanecarboxylate, 96999-01-8, 97%
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Medchemexpress LLC Mpeg-amine (mw 5000) | 80506-64-5 | 99.6% | (C2H4O)nC3H9NO | 100 MG
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mPEG-amine (mPEG-NH2) (MW 5000) is a modifier used to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes by replacing their sulfonic acid portion. It can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS.
- Increases water solubility of dyes
- Forms amide bonds with carboxyl groups
- Suitable for large-scale rotational cytoplasmic flow studies
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