Quinolines and derivatives
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Filtered Search Results
Accela Chembio Inc Ethyl 4-hydroxyquinoline-3-carboxylate | 5g | 26892-90-0 | MFCD00173406 | 97+% | Shelf Life: 2520 Days | Regular
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Ethyl 4-hydroxyquinoline-3-carboxylate | 5g | 26892-90-0 | MFCD00173406 | 97+% | Shelf Life: 2520 Days | Regular
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Ambeed 1HImidazole2carbaldehyde
1H-Imidazole-2-carbaldehyde, 10111-08-7, 95%
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Medchemexpress LLC 1,4,7-trimethyl-1,4,7-triazacyclononane | 96556-05-7 | MFCD00006093 | 98.5% | 171.28 g/mol | C9H21N3 | 5 G
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1,4,7-trimethyl-1,4,7-triazacyclononane is a small cyclic tertiary amine used as a reagent in biochemical assays and as a crosslinking or reactive reagent for research applications.
- used as a reagent in biochemical assays
- serves as a crosslinking or reactive reagent in research
- molecular formula c9h21n3
- molecular weight 171.28 g/mol
- high purity, typically about 98.5%
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Medchemexpress LLC Pacma 31 | 1401089-31-3 | 99.3% | 430.47 g·mol⁻1 | C21H22N2O6S | 100 MG
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PACMA 31 is an irreversible small-molecule inhibitor of protein disulfide isomerase (PDI) used in biochemical and cellular research. It covalently modifies active-site cysteines, has shown tumor-targeting activity in preclinical studies, and contains an alkyne moiety that enables copper-catalyzed azide-alkyne cycloaddition for conjugation and probe development.
- Irreversible inhibitor of protein disulfide isomerase for biochemical and cellular assays.
- Forms covalent bond with active-site cysteines for sustained target engagement.
- Contains an alkyne group suitable for click chemistry conjugation.
- High purity suitable for research use.
- Available in multiple pack sizes for flexible experimental needs.
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TARGETMOL CHEMICALS INC LOC14 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. LOC14 to be the most potent PDI inhibitor reported to date( EC50 500 nM)purity: 98%
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Ambeed 2 4Bromophenyl isoindoline1 3d
2-(4-Bromophenyl)isoindoline-1,3-dione, 40101-31-3, 98%
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TARGETMOL CHEMICALS INC DIRLOTAPIDE 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner possibly by increasing the release of peptide YY into the circulation. purity: 99%
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Apexbio Technology LLC Ro 31-8220 125314-64-9 50mg
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Ro 31-8220 (CAS 125314-64-9) is a potent and selective inhibitor of protein kinase C (PKC) targeting isoforms PKC- (IC50 5 nM) PKC- I (24 nM) PKC- II (14 nM) PKC- (27 nM) and PKC- (24 nM) PKC is a Ca2 and phospholipid-dependent serine/threonine kinase involved in signaling pathways regulating cell proliferation and malignancy Ro 31-8220 modulates downstream signaling by inducing c-Jun expression and activating JNK1 while inhibiting MKP-1 and c-Fos expression independent of PKC activity In immunological studies it suppresses IL-2 production (IC50 80 nM) T cell proliferation (IC50 350 nM) and CD25 expression indicating inhibition of both early and late T cell activation Ro 31-8220 is widely utilized in cellular and molecular studies to dissect PKC-dependent and independent signaling mechanisms
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Ambeed 2 4Bromophenyl isoindoline1 3d
2-(4-Bromophenyl)isoindoline-1,3-dione, 40101-31-3, 98%
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Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 25mg, CAS: 130370-60-4.
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Batimastat (BB-94 CAS 130370-60-4) is a synthetic small-molecule inhibitor targeting matrix metalloproteinases (MMPs) Structurally a polypeptide-like analogue of collagen substrates batimastat contains a peptidic backbone and a hydroxamate moiety that binds the catalytic zinc atom of MMPs It inhibits several MMP subtypes markedly including MMP-1 MMP-2 MMP-3 MMP-7 and MMP-9 with reported IC50 values of 3 4 20 6 and 4 nM respectively In preclinical studies batimastat demonstrates inhibitory effects on tumor growth and angiogenesis across various tumor models including ovarian and colon carcinoma xenografts making it relevant for cancer research and therapeutic development
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Medchemexpress LLC MI-773 | 1303607-07-9 | MFCD28168022 | 96.3% | 562.50 | C29H34Cl2FN3O3 | 10 MG
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MI-773 is a small-molecule inhibitor of the MDM2-p53 protein-protein interaction with high binding affinity for MDM2 and reported antitumor activity in preclinical studies. It is provided as a research-grade compound for use in cancer biology and p53 pathway experiments.
- High-affinity MDM2 binding (reported Kd 8.2 nM).
- Reported antitumor activity in preclinical studies.
- Provided as a research-grade compound suitable for in vitro and in vivo studies.
- Available in small mg-scale quantities for research use.
- Molecular weight 562.50 and formula C29H34Cl2FN3O3 for reference.
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Medchemexpress LLC Tetrabenazine | 200MG
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Tetrabenazine | 200MG
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TARGETMOL CHEMICALS INC Mitoxantrone 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin. Purity 98.74%
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Medchemexpress LLC PH-797804 | 586379-66-0 | 98.9% | 477.30 g·mol⁻¹ | C22H19BrF2N2O3 | 200 MG
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PH-797804 is an ATP-competitive, selective inhibitor of p38 mitogen-activated protein kinases (p38α/p38β) used in research to probe p38-mediated signaling and inflammatory responses. It shows nanomolar biochemical potency and demonstrable cellular activity that reduces LPS-induced cytokine production.
- Selective ATP-competitive p38α/p38β inhibitor.
- Nanomolar biochemical potency (p38α IC50 26 nM; Ki 5.8 nM).
- Demonstrated cellular activity reducing LPS-induced TNF-α and IL-1β release.
- Does not inhibit JNK2, supporting target selectivity.
- High supplied purity and solid white to off-white appearance.
- Suitable for biochemical and cellular assay applications.
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TARGETMOL CHEMICALS INC Allethrin 200MG
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Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. Purity 98.19%
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