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Filtered Search Results
Medchemexpress LLC Lobeglitazone (sulfate) | 763108-62-9 | MFCD28502044 | 99.6% | 578.61 g·mol⁻¹ | C24H26N4O9S2 | 10 MG
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Lobeglitazone sulfate is a thiazolidinedione-class small molecule used for research as a peroxisome proliferator-activated receptor (PPAR) agonist. It has reported activity on PPARγ (EC50 ≈ 137.4 nM) and PPARα (EC50 ≈ 546.3 nM) and is applied in preclinical studies of metabolic, inflammatory, fibrotic, and atherosclerotic pathways. Follow the product SDS for handling and storage instructions.
- Acts as a PPARγ and PPARα agonist with published EC50 values.
- Supports studies of anti-diabetic, anti-inflammatory, and anti-fibrotic mechanisms.
- High purity suitable for biochemical and cellular assays.
- Provided as a sulfate salt to aid solubility in experimental media.
- Stable under recommended storage; consult SDS for solvent storage conditions.
- Supplied in small quantities appropriate for research workflows.
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eMolecules 166388-57-4 | ChemScene | Azido-PEG2-C2-amine | 100mg | 665615397 | CS-0114352 | MFCD13189985 | 174.204 | C6H14N4O2
Medchem Express | PEG3-C4-OBn | 500mg | 515744105 | HY-130620 | 2381196-79-6 | 296.407 | C17H28O4
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Medchemexpress LLC Racemic equol | 94105-90-5 | MFCD00016662 | 99.6% | 242.27 g·mol⁻¹ | C15H14O3 | 200 MG
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Racemic equol is the racemate of equol, a nonsteroidal estrogen receptor ligand and a metabolite of the soy isoflavones daidzin and daidzein. It is commonly used in research on estrogen receptor pharmacology and isoflavone metabolism, with reported EC50 values of 200 nM for ERα and 74 nM for ERβ.
- Racemic mixture of equol suitable for receptor biology studies.
- Shows EC50s of 200 nM (ERα) and 74 nM (ERβ).
- Molecular weight 242.27 g·mol⁻¹ and formula C15H14O3.
- High purity (≈99.6%) for consistent experimental results.
- Solid powder form, stable when stored at low temperatures.
- Available in multiple pack sizes from milligram to gram quantities.
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Medchemexpress LLC Acridine orange 10-nonyl bromide | 75168-11-5 | 99.5% | 472.50 | 25 MG
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Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin with an excitation wavelength (λex) of 489 nm and an emission wavelength (λem) of 525 nm. It is used for research purposes only.
- Fluorescent probe for cardiolipin.
- Can be used to quantify cardiolipin in isolated mitochondria.
- At 4.75 μM, it saturates mitochondrial binding sites in 1.5 X 10^6 cells within 15 minutes at 20°C.
- Upon interaction with cardiolipin, the dye's excitation and emission wavelengths shift from 496 nm and 525 nm to 450 nm and 640 nm, respectively.
- Increasing amounts of cardiolipin (0 to 30 μM) and other acidic phospholipids in thin-walled vesicles, when added to 45 μM Acridine Orange 10-Nonyl Bromide, changes the red fluorescence emission measured at 640 nm according to the liposome composition.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429988 CYANINE5.5 AMINE 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431159 CYANINE5.5 AMINE 5MG
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Medchemexpress LLC Sulfo-Cy3 amine | 2183440-43-7 | 99.7% | 714.93 | 50 MG
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Sulfo-Cy3 amine is a dye derivative of Cyanine 3 that contains an amine group.
- The sulfonate ion enhances the compound's water solubility, making it suitable for aqueous solutions.
- It is a fluorescent dye with a fluorescence spectrum typically ranging from green to orange wavelengths.
- The amine functionality allows it to react with carboxyl groups to form covalent bonds.
- It can bind to biological molecules such as proteins and antibodies, enabling the tracking of their location and dynamic changes in biological samples.
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Accela Chembio Inc 5-aminoisoquinoline | 25g | 1125-60-6 | MFCD00006907 | 98% | Shelf Life: 1980 Days | Light Sensitive/+4
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5-aminoisoquinoline | 25g | 1125-60-6 | MFCD00006907 | 98% | Shelf Life: 1980 Days | Light Sensitive/+4
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000596826 DORDAVIPRONE 200MG
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Medchemexpress LLC Pazopanib (GW786034) | 444731-52-6 | MFCD11616589 | 99.9% | 437.52 g/mol | C21H23N7O2S | 200 MG
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Pazopanib (GW786034) is a small-molecule, multi-target tyrosine kinase inhibitor provided as a research-grade solid. It potently inhibits VEGFR1, VEGFR2, and VEGFR3 and shows activity against PDGFRβ, c-Kit, FGFR1, and c-Fms, with reported IC50 values in the low nanomolar range; it also inhibits VEGF-induced proliferation and VEGFR-2 phosphorylation in HUVEC cells.
- Multi-target VEGFR/PDGFR tyrosine kinase inhibitor
- Potent enzyme inhibition with IC50s: VEGFR1 10 nM, VEGFR2 30 nM, VEGFR3 47 nM
- Cellular activity: inhibits VEGF-induced proliferation and VEGFR-2 phosphorylation (~8 nM)
- High purity (99.9%) solid suitable for research applications
- Available in research packaging sizes including 200 mg
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Medchemexpress LLC Sulfo DBCO-amine | 2028284-70-8 | 99.0% | 100 MG
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Sulfo DBCO-amine is an alkyl chain-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that possess Azide groups. PROTACs themselves are composed of two distinct ligands connected by a linker, with one ligand targeting an E3 ubiquitin ligase and the other targeting a specific protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group for SPAAC with Azide groups
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eMolecules 14510-06-6 | Ambeed | 8-Hydroxyquinoline-2-carbaldehyde | 250mg | 525035238 | A130916 | MFCD00168962 | 173.171 | C10H7NO2
Medchem Express | 2-O4-C-Methyleneuridine | 10mg | 451965695 | HY-111639 | 200435-92-3 | 256.214 | C10H12N2O6
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eMolecules 92-81-9 | 9,10-Dihydroacridine | Combi-Blocks | MFCD00022256 | 181.238 | C13H11N | 98.000 | C1c2ccccc2Nc2ccccc12 | 5g | 495747009
9,10-Dihydroacridine | Combi-Blocks | 92-81-9 | MFCD00022256 | 181.238 | C13H11N | 98.000 | C1c2ccccc2Nc2ccccc12 | 5g | 495747009
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Medchemexpress LLC Ethanamine, 2-(2-azidoethoxy)- | 464190-91-8 | ≥98.0% | C4H10N4O | 250 MG
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Azido-PEG1-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an azide group
- Reacts via copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts via strain-promoted alkyne-azide cycloaddition (SPAAC)
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Medchemexpress LLC Azido-PEG5-amine | 516493-93-9 | 98.0% | C12H26N4O5 | 250 MG
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Azido-PEG5-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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