Quinolines and derivatives

AdipoGen Ethidium bromide Solution

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Chemical. CAS 1239-45-8. Formula C21H20BrN3. MW 394.31. Synthetic. Ethidium bromide EtBr is the most commonly used nucleic acid stain for PAGE or agarose gel electrophoresis. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA and 25-fold on binding double-stranded DNA so that destaining the background is not necessary with a low stain concentration 10 µg/ml. Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids. Ethidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It confers a deep red stain to DNA by acting as an intercalating agent between the starch bases. It has been shown to bind to single-stranded DNA although not as strongly and triple-stranded DNA. Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. It can be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.

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Medchemexpress LLC 3-piperidinecarboxamide, 1-(cyclopropylmethyl)-4-[[[5-(2,4-difluorophenyl)-3-isoxazolyl]carbonyl]am | 2178049-58-4 | 98.8% | 522.55 | C27H28F2N6O3 | 5 MG

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ACT-1004-1239 is a potent, selective, orally active CXCR7 (ACKR3) antagonist supplied for research use. It shows nanomolar potency in biochemical assays and has demonstrated target engagement and pharmacological effects in preclinical models, including modulation of CXCL12/CXCL11 signaling and efficacy in rodent disease models. Supplied formats support both in vitro and in vivo study designs.

• Potent CXCR7 antagonism with reported IC50 of 3.2 nM.
• High purity suitable for research applications.
• Available as solid and 10 mM DMSO solution for convenient use.
• Appropriate for in vitro and in vivo pharmacology studies.
• For research use only; not for human or veterinary use.

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Medchemexpress LLC MEDCHEMEXPRESS LLC

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5000431375 ACRIDINE ORANGE 10-N 50MG

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eMolecules​ Proflavine hemisulfate hydrate | 1811-28-5 | MFCD00149650 | 1g

Combi-Blocks | Proflavine hemisulfate hydrate | 1g | 517032039 | QC-3763 | 95.000 | 1811-28-5 | MFCD00149650 | 534.590 | C26H26N6O5S

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Medchemexpress LLC Acridine orange base | 494-38-2 | 96.58% | 100 MG

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Acridine Orange base is a cell-permeable fluorescent dye utilized for staining various organisms such as bacteria, parasites, and viruses a bright orange. When applied under specific conditions (pH=3.5, Ex=460 nm), it allows for the distinction of human cells, which appear green, through fluorescence microscopy. This dye exhibits green fluorescence when bound to double-stranded DNA (dsDNA) and red fluorescence when bound to single-stranded DNA (ssDNA) or single-stranded RNA (ssRNA), making it suitable for cell cycle assays.

• Cell-permeable fluorescent dye.
• Stains organisms bright orange.
• Distinguishes human cells in green.
• Fluoresces green with dsDNA.
• Fluoresces red with ssDNA or ssRNA.
• Useful for cell cycle assays.

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Medchemexpress LLC 3,6-Acridinediamine, N3,N3,N6,N6-tetramethyl- | 494-38-2 | 96.58% | 500 MG

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Acridine Orange base is a cell-permeable fluorescent dye. It stains various organisms such as bacteria, parasites, and viruses bright orange. When used under appropriate conditions (pH=3.5, Ex=460 nm), it can distinguish human cells in green for detection by fluorescence microscopy. This dye fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644). It can also be utilized in cell cycle assays.

• Cell-permeable fluorescent dye.
• Stains organisms bright orange.
• Distinguishes human cells in green under specific conditions.
• Fluoresces green when bound to dsDNA.
• Fluoresces red when bound to ssDNA or ssRNA.
• Can be used in cell cycle assays.

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Medchemexpress LLC DTPD-Q | 252950-56-4 | 99.7% | 318.37 | 5 MG

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DTPD-Q is a transformation product of the tire additive N,N′-diphenyl-p-phenylenediamine (DTPD). It accumulates and increases ecological risk in the environment.

• For research use only.
• Appearance: Solid.
• Color: Yellow to brown.

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Medchemexpress LLC 6PPD-Q | 2754428-18-5 | C18H22N2O2 | 100 MG

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6PPD-Q | 2754428-18-5 | C18H22N2O2 | 100 MG

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Medchemexpress LLC MEDCHEMEXPRESS LLC

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5000428994 Q AGAROSE 6FF 25ML

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