Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,021 – 1,035 of 3,717 results

1,021

Apexbio Technology LLC Matrine(Synonyms: Sophocarpidine, Matridin, (-)-Matrine, α-Matrine, (−)-α-Matrine, L-Matrine, Kushenin), 200mg, CAS: 519-02-8.

Matrine (CAS 519-02-8) is an alkaloid derived from plants in the Sophora genus with demonstrated anticancer and anti-inflammatory activities It functions in part through agonism of kappa-opioid and possibly other receptors Matrine inhibits the MNK45 gastric cancer cell line proliferation (IC50 540 g/ml MTT assay) by modifying protein expression profiles (e g NF- B XIAP CIAP p-ERK) In vitro matrine induces apoptosis in NSCLC cells through ROS generation caspase activation and p38 pathway modulation Animal studies suggest therapeutic roles in cardiac injury and sepsis-related lung inflammation

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1,022

Medchemexpress LLC Prostaglandin H2 | 42935-17-1 | ≥95.0% | 352.47 | 100 UG

Prostaglandin H2 (PGH2) is an endothelium-derived contracting factor that causes vasoconstriction. It is a common precursor of all prostaglandins, produced by cells expressing cyclooxygenases. PGH2 activates PGD2 receptors, induces eosinophil migration, inhibits platelet aggregation, and accelerates the formation of amyloid β1-42 oligomers. It is used in research for inflammation and neurological diseases, such as Alzheimer's disease.

Increases forward-scatter of eosinophils.
Induces shape changes and calcium production in eosinophils.
Induces migration and collagen-induced platelet aggregation in eosinophils.
Inhibits eosinophil degranulation by activating CRTH2 receptors.
Accelerates the rate of formation of dimers and higher oligomers of amyloid β1-42.
Induces contraction of rabbit pulmonary artery.

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1,023

Medchemexpress LLC Sulfo-cyanine3 azide (potassium) | 1658416-54-6 | 95.3% | 10 MG

Sulfo-cyanine3 azide (potassium) is a water-soluble, sulfonated cyanine fluorescent azide for bioorthogonal labeling via azide-alkyne click chemistry. It exhibits Cy3-like optical properties with excitation/emission near 548/563 nm, and is supplied as a potassium salt with a certificate of analysis for documented purity.

Cy3-like excitation/emission (548/563 nm).
Water-soluble sulfonated dye for aqueous labeling.
Reactive azide group for azide-alkyne click chemistry.
Supplied as a potassium salt with certificate of analysis and documented purity.
Suitable for labeling proteins, peptides, and oligonucleotides.

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1,024

eMolecules 3-Quinolinecarboxylic acid, 4-hydroxy-6,8-dimethyl-, ethyl ester | 77156-77-5 | MFCD02081544 | 5g

WuXi ChemSupply | 3-Quinolinecarboxylic acid, 4-hydroxy-6,8-dimethyl-, ethyl ester | 5g | 599165295 | LN00179016 | 95.000 | 77156-77-5 | MFCD02081544 | 245.278 | C14H15NO3

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1,025

Medchemexpress LLC Anhydrous sodium dihydrogen phosphate | 7558-80-7 | 99.1% | 500 G

Anhydrous sodium dihydrogen phosphate | 7558-80-7 | 99.1% | 500 G

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1,026

Medchemexpress LLC Anhydrous sodium dihydrogen phosphate, for molecular biology | 7558-80-7 | 99.9% | 100 G

Anhydrous sodium dihydrogen phosphate, for molecular biology is an inorganic salt compound that can be used as a buffer and nutritional supplement in molecular biology experiments. It is also used in industry and laboratories as a buffer, nutritional supplement, cleaning agent, and in metal processing, pharmaceutical, chemical industries, water treatment, and environmental protection (as a purifying agent or precipitating agent for solutions).

Used as a buffer
Functions as a nutritional supplement
Employed as a cleaning agent
Utilized in metal processing
Applicable in pharmaceutical and chemical industries
Used in water treatment and environmental protection as a purifying or precipitating agent

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1,027

Medchemexpress LLC Amine-PEG-amine (MW 5000) | 95.0% | 100 MG

Amine-PEG-amine (MW 5000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds consisting of two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. The product is intended for research use only.

PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins
Intended for research use only
Solid appearance
White to off-white color
Molecular weight of 5000 (average)
95.0% purity

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1,028

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000341828 CEPHRADINE MONOHYDR 500MG

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1,029

eMolecules Pharmablock 7-bromoisoquinoline 25mg 551259458 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN

Pharmablock 7-bromoisoquinoline 25mg 551259458 PBN2011270 0 000 58794-09-5 MFCD07368661 208 058 C9H6BrN

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1,030

Ambeed 4Aminoisophthalic acid

4-Aminoisophthalic acid, 33890-03-8, 98%

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1,031

Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 250 MG

Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker used in the synthesis of PROTACs. PROTACs, or Proteolysis-targeting chimeras, consist of two different ligands connected by a linker. One ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PEG-based (8 units) linker
Can be used in the synthesis of PROTACs
Ligands connected by a linker target E3 ubiquitin ligase and protein of interest
Utilizes intracellular ubiquitin-proteasome system to selectively degrade target proteins

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1,032

Apexbio Technology LLC APEXBIO TECHNOLOGY LLC

5000568632 CYCLEN-200MG

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1,033

Ambeed 5Methoxy2nitrobenzaldehyde

5-Methoxy-2-nitrobenzaldehyde, 20357-24-8, 98%

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1,034

Ambeed 1 3Diphenylpropan2amine

1,3-Diphenylpropan-2-amine, 4275-43-8, 97%

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1,035

AdipoGen Ethidium bromide Solution

Chemical. CAS 1239-45-8. Formula C21H20BrN3. MW 394.31. Synthetic. Ethidium bromide EtBr is the most commonly used nucleic acid stain for PAGE or agarose gel electrophoresis. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA and 25-fold on binding double-stranded DNA so that destaining the background is not necessary with a low stain concentration 10 µg/ml. Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids. Ethidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It confers a deep red stain to DNA by acting as an intercalating agent between the starch bases. It has been shown to bind to single-stranded DNA although not as strongly and triple-stranded DNA. Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. It can be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.

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Quinolines and derivatives

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Apexbio Technology LLC Matrine(Synonyms: Sophocarpidine, Matridin, (-)-Matrine, α-Matrine, (−)-α-Matrine, L-Matrine, Kushenin), 200mg, CAS: 519-02-8. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Prostaglandin H2 | 42935-17-1 | ≥95.0% | 352.47 | 100 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfo-cyanine3 azide (potassium) | 1658416-54-6 | 95.3% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Anhydrous sodium dihydrogen phosphate | 7558-80-7 | 99.1% | 500 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Anhydrous sodium dihydrogen phosphate, for molecular biology | 7558-80-7 | 99.9% | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amine-PEG-amine (MW 5000) | 95.0% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC APEXBIO TECHNOLOGY LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

AdipoGen Ethidium bromide Solution Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More