Quinolines and derivatives
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Filtered Search Results
Apexbio Technology LLC NP118809 41332-24-5 200mg
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NP118809 (CAS 41332-24-5) is a potent and selective blocker of N-type voltage-gated calcium channels exhibiting an IC50 of 0 11 M in vitro It demonstrates significant selectivity over L-type calcium channels with over 100-fold preference (L-type IC50 12 2 M) In vivo studies in rats indicate that NP118809 is orally bioavailable (mean 30%) with a Tmax of 2 3 hours and a half-life of 2 1 hours following intravenous or oral administration The compound exhibits wide tissue distribution and has been shown to produce analgesic effects in animal pain models NP118809 is useful for research into N-type calcium channel function and modulation particularly in studies of pain signaling and neuropharmacology
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Apexbio Technology LLC CYT387 1056634-68-4 200mg
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CYT387 (CAS 1056634-68-4) is an aminopyrimidine derivative identified through high-throughput screening and optimized with structure-guided medicinal chemistry It functions as an inhibitor targeting Janus kinase family enzymes JAK1 JAK2 JAK3 and TYK2 with reported IC50 values of 11 nM 18 nM 155 nM and 17 nM respectively At concentrations between 500 1500 nM CYT387 selectively suppresses JAK2 signaling inhibits proliferation of JAK2-dependent hematopoietic cell lines and induces apoptosis with minimal effects on non-hematopoietic cells CYT387 is employed in experimental studies of JAK2-mediated signaling pathways and myeloproliferative neoplasms
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eMolecules EMOLECULES INC
5000491361 4-CHLORO-3-NITROQUINOLINE 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000427390 CINCHONIDINE 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000427868 CINCHONIDINE 500MG
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568642 QUINIDINE-SULFATE-250MG
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Chemscene CHEMSCENE
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5000579330 HYDROQUINIDINE 10G
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Chemscene CHEMSCENE
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5000579432 HYDROQUINIDINE 25G
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American Radiolabeled Chemicals Inc QUINIDINE 9-3H 250 UCI
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NC3672958 QUINIDINE 9-3H 250 UCI
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Medchemexpress LLC Quinidine methiodide | 42982-87-6 | C21H27IN2O2 | 25 MG
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Quinidine methiodide is a metabolite of Quinidine, an antiarrhythmic agent, intended for research use only. This high-purity product, appearing as a white to light yellow solid, requires specific storage conditions to maintain its integrity.
- Metabolite of Quinidine, an antiarrhythmic agent
- For research use only
- Purity of 99.75%
- Solid, white to light yellow appearance
- Optimal storage at -20°C under nitrogen, away from moisture
- Solvent storage at -80°C for 6 months or -20°C for 1 month under nitrogen, away from moisture
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Medchemexpress LLC Quinidine methiodide | 42982-87-6 | C21H27IN2O2 | 50 MG
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Quinidine methiodide is a metabolite of Quinidine, an antiarrhythmic agent. This product is intended for research use only.
- High purity: 99.75%
- Available in solid form
- Soluble in DMSO for in vitro studies
- Soluble in various mixtures for in vivo studies
- Store solid at -20°C under nitrogen
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Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 1 ML
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Mefloquine is an orally active and potent quinoline antimalarial agent that also acts as an anti-SARS-CoV-2 entry inhibitor. It is used in research for:
- K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM.
- Malaria studies.
- Systemic lupus erythematosus research.
- Cancer research.
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AdipoGen Quinine anhydrous
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Chemical. CAS 130-95-0. Formula C20H24N2O2. MW 324.42. Synthetic. Because of its relatively constant and well-known fluorescence quantum yield, quinine is also used in photochemistry as a common fluorescence standard. It has been used for imaging of oxygen evolution and oxide formation. Chloride and bromide have been shown to quench fluorescence. Generally it is famous as potassium channel blocker with antipyretic fever-reducing, antimalarial, analgesic painkilling, and anti-inflammatory properties.
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Chemscene CHEMSCENE
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5000579530 RESIQUIMOD 25MG
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Medchemexpress LLC Imiquimod | 99011-02-6 | 100.0% | 200 MG
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Imiquimod is an immune response modifier that functions as a selective Toll-like Receptor 7 (TLR7) agonist. It demonstrates antiviral and antitumor effects in living organisms.
- Selective TLR7 agonist.
- Exhibits antiviral and antitumor properties in vivo.
- Used for research related to external genital and perianal warts, cancer, and COVID-19.
- Purity: 99.96%.
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