Quinolines and derivatives
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Apexbio Technology LLC OR-486 7659-29-2 50mg
OR-486 is a small-molecule inhibitor targeting catechol-O-methyltransferase (COMT) It is designed to inhibit COMT activity thereby blocking the enzyme-mediated methylation of catecholamine substrates and regulating neurotransmitter pathways OR-486 exerts its biological activity primarily through enzyme inhibition In biochemical assays OR-486 demonstrates potent inhibitory activity with an IC50 value of approximately 12 nM Based on these pharmacological properties OR-486 holds research potential in investigating catecholamine metabolism neurotransmitter regulation and studies of neuronal pathways as well as serving as a ligand for synthesizing molybdenum(VI)-based metal complexes
