Quinolines and derivatives
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Apexbio Technology LLC Oxaliplatin 61825-94-3 200mg
Oxaliplatin (CAS 61825-94-3) is a platinum-based chemotherapeutic agent that functions primarily by forming DNA adducts thereby disrupting DNA synthesis and ultimately inducing apoptosis via primary and secondary DNA damage It demonstrates antitumor activity against various cancer cell lines including melanoma (IC50 0 14 7 85 M) ovarian carcinoma (IC50 0 17 M) bladder cancer (IC50 11 15 M) colon cancer (IC50 2 95 M) and glioblastoma (IC50 17 6 30 9 M) Oxaliplatin is useful in preclinical animal tumor models and has clinical applications notably in metastatic colorectal cancer therapy combined with fluorouracil and folinic acid
