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Tetrahydroisoquinolines

Organic heterocyclic compounds that consist of an isoquinoline ring with no double bonds; contains a benzene ring fused to a six-membered ring with one nitrogen atom and five carbon atoms.

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1

eMolecules​ (1-BENZYL-1,2,3,6-TETRAHYDROPYRIDIN-4-YL)METHANOL | 158984-76-0 | MFCD16620244 | 1g

AstaTech | (1-BENZYL-1,2,3,6-TETRAHYDROPYRIDIN-4-YL)METHANOL | 1g | 248485036 | AB6331 | 95.000 | 158984-76-0 | MFCD16620244 | 203.285 | C13H17NO

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2

Medchemexpress LLC Olodanrigan | 1316755-16-4 | 98.9% | 100 MG
SDP

Olodanrigan (EMA401) is a highly selective, orally active, and peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. This compound is currently under development as a therapeutic agent for neuropathic pain. Its analgesic action is attributed to the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, which effectively inhibits both DRG neuron hyperexcitability and the sprouting of DRG neurons.

  • Highly selective AT2 receptor antagonist
  • Orally active and peripherally restricted
  • A therapeutic agent candidate for neuropathic pain
  • Inhibits p38 and p42/p44 MAPK activation
  • Prevents DRG neuron hyperexcitability and sprouting
  • Purity of 98.9%
  • Store powder at -20°C for 3 years or 4°C for 2 years
  • Store in solvent at -80°C for 2 years or -20°C for 1 year

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