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Tafluprost ethyl amide is a prostaglandin derivative used in research to reduce intraocular pressure and to investigate effects on eyelash growth. Supplied for research use only, it is intended for pharmacological and preclinical ophthalmic studies involving prostaglandin receptor activity.
Reduces intraocular pressure in experimental settings.
Influences eyelash growth pathways for cosmetic and biological research.
High reported purity suitable for analytical and preclinical work.
Offered in multiple small-scale package sizes for laboratory use.
Stable under recommended storage conditions when protected from light.
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Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide (HY-P10138). It acts as a high-affinity antagonist of the human GIP receptor in vitro. This compound shows potential for anti-obesity and anti-diabetic effects.
High affinity antagonist of the human GIP receptor in vitro.
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N-Boc-dolaproine-amide-Me-Phe is an amino acid residue of the pentapeptide Dolastatin 10, which is known for its ability to inhibit tubulin polymerization and mitosis, demonstrating anticancer activity.
Amino acid residue of the pentapeptide Dolastatin 10.
Dolastatin 10 inhibits tubulin polymerization and mitosis.
Exhibits anticancer activity.
Intended for research use only.
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Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide (HY-P10138). It is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide TFA has potential anti-obesity and anti-diabetic effects.
High affinity antagonist of the human GIP receptor in vitro.
Potential anti-obesity effects.
Potential anti-diabetic effects.
Competitively binds to GIP receptor (GIPR), blocking GIP-mediated cAMP accumulation (Ki=16.8 nM), β-arrestin recruitment (Ki for β-arrestin-1/2 recruitment is 10.6 nM and 10.2 nM) and receptor internalization.
Inhibits GIP mediated insulin secretion and signal transduction in adipocytes.
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Fluorescein-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Intended for research use only
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AMI-1 (CAS 20324-87-2) is a small molecule inhibitor of protein arginine N-methyltransferase 1 (PRMT1) exhibiting an IC50 of 8 8 M It acts by preventing the binding of peptide substrates to PRMT1 without interfering with the S-adenosyl-L-methionine (SAM) cofactor binding site In addition to its action on PRMT1 AMI-1 inhibits HIV-1 reverse transcriptase polymerase activity with an IC50 of 5 0 M AMI-1 is cell-permeable facilitating its use in cellular studies investigating arginine methylation epigenetic regulation and viral replication
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