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AMI-1 is a cell-permeable, reversible small-molecule inhibitor of protein arginine N-methyltransferases (PRMTs). It blocks peptide-substrate binding and is used in biochemical and cellular studies to probe arginine methylation and PRMT function.
Purity: 98.0%.
Molecular weight: 548.45 g·mol⁻1.
CAS number: 20324-87-2.
Chemical formula: C21H14N2Na2O9S2.
Pack size: 10 MG.
Storage: sealed, away from moisture; in solution, -80°C up to 2 years or -20°C up to 1 year.
Targets: inhibits PRMT1, PRMT3, PRMT4, PRMT6, PRMT5, and yeast Hmt1p.
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Thieno-CTP is a structural analog of cytidine triphosphate (CTP) that incorporates a thiophene-modified nucleobase allowing incorporation into RNA by RNA polymerases during transcription Following enzymatic incorporation into nascent RNA transcripts the introduced thienyl modification acts as a reactive site suitable for subsequent bioorthogonal labeling via selective chemical reactions This chemical feature enables detection visualization and analysis of newly synthesized RNA molecules within biological systems Hence Thieno-CTP is utilized to examine transcriptional dynamics RNA synthetic regulation RNA trafficking and RNA-protein interaction studies supporting research into RNA biology and related areas
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Hydrochloride salt of a small-molecule research compound (CAS 2380273-26-5) supplied as a white to yellow solid for laboratory use. COA and SDS report purity 98.59% and provide storage and hazard guidance.
Hydrochloride salt, solid form.
Purity 98.6% (LCMS, COA).
Molecular weight 481.05 g/mol.
Chemical formula C23H33ClN4O3S.
Recommended storage: -20°C; protect from moisture and light.
Hazard statements: harmful if swallowed; causes skin and eye irritation; may cause respiratory irritation.
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