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Cayman Chemical 4-ThIouracIl 500mg
A dual inhibitor of IGF-1R kinase and IR (IC50s 100 and 73 nM respectively) blocks IFG-1R autophosphorylation and signaling through MEK1/2 and Akt leading to G1 arrest and apoptosis in ML-1 cells reverses EMT in MCF10A cells overexpressing constitutively activated IGF-1R
