Thiophenes
Medchemexpress LLC 5-Methyl-2-thiophenecarboxaldehyde | 13679-70-4 | 99.9% | 126.18 | 100 G
5-Methyl-2-thiophenecarboxaldehyde acts as a candidate to microscopic third order non-linear optical (NLO) material. It is also an analytical standard intended for research and analytical applications.
- Acts as a candidate to microscopic third order non-linear optical (NLO) material.
- Analytical standard for research and analytical applications.
Apexbio Technology LLC Pramipexole dihydrochloride 104632-25-9 10mM (in 1mL DMSO)
Pramipexole dihydrochloride is a small-molecule agonist targeting dopamine receptors exhibiting selective affinity toward the D3 dopamine receptor subtype and lower affinity for the D2L D2S and D4 subtypes It is designed to stimulate dopamine receptor-mediated signaling thereby modulating dopaminergic pathways involved in motor function Pramipexole dihydrochloride exerts its biological activity primarily through dopamine receptor agonism and also demonstrates receptor-independent neuroprotective effects by attenuating mitochondrial reactive oxygen species (ROS) production and decreasing apoptosis-related signaling cascades Based on these pharmacological properties pramipexole dihydrochloride holds research potential in exploring dopaminergic system involvement and neuroprotective mechanisms relevant to neurodegenerative conditions such as Parkinson s disease and restless legs syndrome
Apexbio Technology LLC GSK-LSD1 2HCl 2102933-95-7 5mg
GSK-LSD1 2HCl (CAS 2102933-95-7) is a selective irreversible inhibitor of lysine-specific demethylase 1A (LSD1) a flavin-dependent histone demethylase that modulates mono- and dimethylated lysine residues and is implicated in processes such as oocyte growth and tissue-specific differentiation GSK-LSD1 2HCl inhibits LSD1 with an IC50 of 16 nM and exhibits over 1000-fold selectivity against related FAD-utilizing enzymes including LSD2 MAO-A and MAO-B In cancer cell lines it demonstrates EC50 values below 5 nM for both gene expression modulation and growth inhibition GSK-LSD1 2HCl serves as a valuable chemical probe in epigenetics and cancer research
eMolecules Synthonix / 3-aminothiophene-2-carboxamide / 5g / 784552335 / AC77867 / / 147123-47-5 / MFCD00052593 / 142.180 / C5H6N2OS
Synthonix / 3-aminothiophene-2-carboxamide / 5g / 784552335 / AC77867 / / 147123-47-5 / MFCD00052593 / 142.180 / C5H6N2OS
Medchemexpress LLC Puromycin dihydrochloride | 58-58-2 | MFCD00012691 | 99.9% | 500 MG
Puromycin dihydrochloride is an aminonucleoside antibiotic that inhibits protein synthesis. It blocks protein synthesis after aminoacyl-sRNA formation, leading to the accumulation of small peptides. It induces premature termination of translation by serving as an acceptor substrate and by competing with aminoacyl-tRNA for binding to the A' site. This allows for direct evaluation of translation activity in single cells using immunofluorescence microscopy and in heterogeneous cell populations via fluorescence-activated cell sorting.
- Aminonucleoside antibiotic
- Inhibits protein synthesis
- Blocks protein synthesis after aminoacyl-sRNA formation
- Leads to the accumulation of small peptides
- Causes premature termination of translation
- Allows direct evaluation of translation activity in single cells by immunofluorescence microscopy and in heterogeneous cell populations by fluorescence-activated cell sorting
eMolecules 6165-68-0 | Thiophen-2-ylboronic acid | Ambeed | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 552669677
Thiophen-2-ylboronic acid | Ambeed | 6165-68-0 | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 552669677
eMolecules 6165-68-0 | Thiophene-2-boronic acid | Apollo Scientific | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 562435432
Thiophene-2-boronic acid | Apollo Scientific | 6165-68-0 | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 562435432
Medchemexpress LLC Gyki 52466 dihydrochloride | 2319722-40-0 | 99.8% | 366.24 | C17H17Cl2N3O2 | 50 MG
GYKI 52466 dihydrochloride is a selective, noncompetitive antagonist of AMPA and kainate ionotropic glutamate receptors used in preclinical neuroscience research. It is orally active, shows blood-brain barrier permeability, and has demonstrated anticonvulsant and neuroprotective effects in animal studies. Supplied as a solid for laboratory use.
- Selective noncompetitive AMPA and kainate receptor antagonist.
- Orally active with blood-brain barrier permeability.
- Demonstrated anticonvulsant and neuroprotective effects in preclinical studies.
- Supplied as a yellow to orange solid for laboratory use.
- Store sealed, away from moisture and light; in solvent store at -80°C (6 months) or -20°C (1 month).
Apexbio Technology LLC Pramipexole 2HCl Monohydrate 191217-81-9 10mM (in 1mL DMSO)
Pramipexole 2HCl Monohydrate is a synthetic non-ergoline dopamine receptor agonist targeting dopamine receptor subtypes particularly D3 D2S D2L and D4 It is designed to activate these receptors thereby modulating dopaminergic transmission pathways Pramipexole 2HCl Monohydrate exerts its biological activity primarily through selective receptor activation Based on these pharmacological properties Pramipexole 2HCl Monohydrate holds research potential in studies of receptor-ligand interactions receptor subtype functional analysis and dopamine-related neurologic or psychiatric disorders including Parkinson s disease and restless legs syndrome
Aobchem 2-(4-Bromo-5-methylthiophene-2-yl)-1 3-dioxolane | ≥97% | CAS 479196-49-1 | C8H9BrO2S | 500mg
2-(4-Bromo-5-methylthiophene-2-yl)-1 3-dioxolane | ≥97% | CAS 479196-49-1 | C8H9BrO2S | 500mg
Aobchem 2-(Thiophen-2-yl)quinazolin-4-ol | ≥95% | CAS 26059-85-8 | C12H8N2OS | 500mg
2-(Thiophen-2-yl)quinazolin-4-ol | ≥95% | CAS 26059-85-8 | C12H8N2OS | 500mg