Thiophenes

Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms, and one sulfur atom.

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2,491 – 2,505 of 4,393 results

2,491

Medchemexpress LLC DRB18 | 2863686-81-9 | 99.6% | C22H23ClN2O2 | 100 MG

DRB18 is a potent pan-class GLUT inhibitor that alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. It can lead to G1/S phase arrest, increase oxidative stress, and cause necrotic cell death, while also exhibiting anti-tumor activity.

Potent pan-class GLUT inhibitor
Alters energy-related metabolism in A549 cells
Leads to G1/S phase arrest
Increases oxidative stress
Causes necrotic cell death
Exhibits anti-tumor activity
Reduces glucose uptake in GLUT1-4-expressed HEK293 cell lines
Decreases expression of GLUT1-4 in xenografted tumors
Reduces proliferative capacity within xenografted tumors

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2,492

eMolecules 17266-30-7 | 5-Chlorobenzo[b]thiophene-3-acetic acid | Combi-Blocks | MFCD00052308 | 226.670 | C10H7ClO2S | 97.000 | OC(=O)Cc1csc2ccc(Cl)cc12 | 1g | 448006966

5-Chlorobenzo[b]thiophene-3-acetic acid | Combi-Blocks | 17266-30-7 | MFCD00052308 | 226.670 | C10H7ClO2S | 97.000 | OC(=O)Cc1csc2ccc(Cl)cc12 | 1g | 448006966

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2,493

eMolecules 13138-70-0 | Ambeed | 4-Nitrothiophene-2-carboxylic acid | 100mg | 598441848 | A131336 | MFCD07787605 | 173.14 | C5H3NO4S

ChemScene | 5-Bromo-N6-dimethylpyridin-2-amine | 100mg | 712839000 | CS-0380665 | 155789-98-3 | MFCD21784562 | 201.067 | C7H9BrN2

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2,494

eMolecules 57500-53-5 | ChemScene | 4-Nitrothiophene-2-carbaldehyde | 100mg | 665615542 | CS-0008649 | MFCD01859813 | 157.14 | C5H3NO3S

ChemScene | 4-Nitrothiophene-2-carbaldehyde | 100mg | 665615542 | CS-0008649 | 57500-53-5 | MFCD01859813 | 157.140 | C5H3NO3S

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2,495

eMolecules 41498-07-1 | 4-Bromo-5-nitrothiophene-2-carbaldehyde | MFCD11865195 | 1g

ChemScene | 6-Bromo-2-methylquinoline-3-carboxylic acid | 250mg | 572182301 | CS-0063919 | 92513-39-8 | MFCD09787811 | 266.094 | C11H8BrNO2

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2,496

Ambeed AMBEED

5000867692 2-CHLORO-3-NITROTHIOPHENE 1GR

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2,497

Aobchem Benzo[b]thiophene-2-carboxylic acid 5-cyano- ethyl ester | ≥97% | CAS 105191-14-8 | C12H9NO2S | 1g

Benzo[b]thiophene-2-carboxylic acid 5-cyano- ethyl ester | ≥97% | CAS 105191-14-8 | C12H9NO2S | 1g

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2,498

Aobchem 5-Bromo-2 3-dichlorothiophene | ≥95% | CAS 83663-36-9 | C4HBrCl2S | 1g

5-Bromo-2 3-dichlorothiophene | ≥95% | CAS 83663-36-9 | C4HBrCl2S | 1g

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2,499

Aobchem 4-Bromo-2-chloro-6-fluorobenzoic acid | ≥97% | CAS 1321613-01-7 | C7H3BrClFO2 | 5g

4-Bromo-2-chloro-6-fluorobenzoic acid | ≥97% | CAS 1321613-01-7 | C7H3BrClFO2 | 5g

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2,500

Aobchem Benzo[b]thiophene-2-carboxylic acid 5-cyano- ethyl ester | ≥97% | CAS 105191-14-8 | C12H9NO2S | 5g

Benzo[b]thiophene-2-carboxylic acid 5-cyano- ethyl ester | ≥97% | CAS 105191-14-8 | C12H9NO2S | 5g

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2,501

Medchemexpress LLC SKLB325 | 66680-03-3 | 99.2% | 244.25 | 100 MG

SKLB325 is a Jumonji domain-containing 6 (JMJD6) inhibitor with a binding affinity (KD) value of 0.755 μM and an IC50 value of 0.7797 μM. It exhibits antitumor effects on ovarian cancer in vivo and in vitro, and induces apoptosis. It also shows remarkable antitumor efficacy in renal cell carcinoma (RCC).

Inhibits proliferation and induces apoptosis and cell death in ovarian cancer cells.
Plays a significant role in inhibiting tumor growth by inhibiting angiogenesis.
Upregulates the expression of p53 and its downstream effectors at both mRNA and protein levels.
Demonstrates antitumor activities in an intraperitoneal xenograft model.
Prolongs the survival of tumor-bearing mice without obvious side effects.
Effective in suppressing tumor growth in nude mice.

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2,502

Aobchem Methyl 4-bromo-7-fluorobenzo[b]thiophene-2-carboxylate | ≥97% | CAS 360576-05-2 | C10H6BrFO2S | 1g

Methyl 4-bromo-7-fluorobenzo[b]thiophene-2-carboxylate | ≥97% | CAS 360576-05-2 | C10H6BrFO2S | 1g

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2,503

Aobchem 3-Bromo-4-chloro-2-fluorobenzonitrile | ≥97% | CAS 2092624-38-7 | C7H2BrClFN | 250mg

3-Bromo-4-chloro-2-fluorobenzonitrile | ≥97% | CAS 2092624-38-7 | C7H2BrClFN | 250mg

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2,504

Aobchem 5-Bromo-2-chloro-3-fluorobenzoic acid | ≥97% | CAS 1498945-58-6 | C7H3BrClFO2 | 250mg

5-Bromo-2-chloro-3-fluorobenzoic acid | ≥97% | CAS 1498945-58-6 | C7H3BrClFO2 | 250mg

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2,505

Aobchem 2-Bromo-3-ethoxy-6-fluorobenzoic acid | ≥97% | CAS 2384511-09-3 | C9H8BrFO3 | 250mg

2-Bromo-3-ethoxy-6-fluorobenzoic acid | ≥97% | CAS 2384511-09-3 | C9H8BrFO3 | 250mg

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Thiophenes

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Medchemexpress LLC DRB18 | 2863686-81-9 | 99.6% | C22H23ClN2O2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SKLB325 | 66680-03-3 | 99.2% | 244.25 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DRB18 | 2863686-81-9 | 99.6% | C22H23ClN2O2 | 100 MG

Medchemexpress LLC SKLB325 | 66680-03-3 | 99.2% | 244.25 | 100 MG