Thiophenes
Selleck Chemical LLC Trifluoperazine 2HCl S3201-1g
Trifluoperazine (NSC-17474 RP-7623 SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1 1 nM Trifluoperazine also inhibits calmodulin (CaM)
Medchemexpress LLC 2-undecyl-4R-thiazolidinecarboxylic acid | 298186-80-8 | ≥98.0% | 5 MG
CAY10444 (BML-241) is a small-molecule antagonist of the sphingosine-1-phosphate receptor 3 (S1P3), used as a research reagent to study S1P3-mediated calcium mobilization and related cellular responses in vitro.
- Antagonist of S1P3, used in cell-based calcium and migration assays.
- High purity: ≥98.0%.
- Molecular weight 287.5 g/mol; formula C15H29NO2S.
- Crystalline solid; store at -20°C.
- Supplied as a small research vial (typical single-vial quantity: 5 mg).
Selleck Chemical LLC Cyclizine 2HCl S4139-50mg
Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity
Apexbio Technology LLC Clozapine N-oxide(CNO) dihydrochloride(Synonyms: CNO dihydrochloride, Clozapine N-oxide hydrochloride,Clozapine N-oxide dihydrochloride), 25mg, CAS: 2250025-93-3.
Clozapine N-oxide (CNO) dihydrochloride (CAS 2250025-93-3) is a synthetic metabolite derived from clozapine commonly utilized as an agonist for designer receptors exclusively activated by designer drugs (DREADDs) In neuroscience research CNO selectively binds and activates engineered muscarinic receptors particularly hM3Dq and hM4Di thereby influencing neuronal signaling upon penetrating the blood-brain barrier Due to its specificity CNO dihydrochloride serves as a valuable tool for dissecting neuronal circuits and elucidating their functional roles in behavioral studies
Medchemexpress LLC PKSI-527 | 128837-71-8 | MFCD01745772 | >98.0% | 473.99 g/mol | C25H32ClN3O4 | 10MM 1ML
PKSI-527 is a selective small-molecule inhibitor of plasma kallikrein used in biochemical and pharmacological research. It has been reported to suppress collagen-induced arthritis by modulating the kallikrein-kinin system and is supplied as a hydrochloride salt suitable for in vitro and in vivo studies.
- Selective plasma kallikrein inhibitor.
- Demonstrated activity in collagen-induced arthritis models.
- Supplied as the hydrochloride salt for improved stability and handling.
- High solubility in DMSO; typical stock solutions prepared at 1 mM, 5 mM, or 10 mM.
- Storage recommendations for powder and solutions to preserve stability.
- Reported purity greater than 98% by some suppliers.
- Molecular weight 473.99 g/mol; chemical formula C25H32ClN3O4.
eMolecules 5-(Methylthio)thiophene-2-carboxylic acid | 20873-58-9 | MFCD00173742 | 5g
Combi-Blocks | 5-(Methylthio)thiophene-2-carboxylic acid | 5g | 482934530 | QG-0377 | 97.000 | 20873-58-9 | MFCD00173742 | 174.230 | C6H6O2S2
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Apexbio Technology LLC H 89 2HCl 130964-39-5 50mg
H 89 2HCl (CAS 130964-39-5) is a small-molecule inhibitor targeting cyclic AMP-dependent protein kinase (PKA) It exhibits a Ki of approximately 48 nM toward PKA and demonstrates substantial selectivity compared to related kinases such as PKG (about 10-fold) PKC MLCK calmodulin kinase II and casein kinases (approximately 500-fold) In PC12D cells H 89 at micromolar concentrations suppresses forskolin-induced phosphorylation events and neurite outgrowth without altering intracellular cAMP levels Due to its selective inhibitory profile H 89 is widely utilized in cell signaling studies examining cAMP-dependent pathways
Medchemexpress LLC Pksi-527 | 128837-71-8 | MFCD01745772 | 98.1% | 473.99 | C25H32ClN3O4 | 25MG
PKSI-527 is a research compound that functions as a highly selective plasma kallikrein inhibitor. It has been reported to suppress collagen-induced arthritis by modulating the kallikrein-kinin system and is provided with sufficient analytical purity for biological research applications.
- Selective plasma kallikrein inhibitor.
- Reported to suppress collagen-induced arthritis in preclinical models.
- Purity 98.08% as supplied for research use.
- Chemical formula C25H32ClN3O4, molecular weight 473.99.
- Soluble in DMSO at 100 mg/mL (≈210.97 mM); ultrasonic agitation recommended.
- Intended for use in biochemical and pharmacological studies of the kallikrein-kinin pathway.
Medchemexpress LLC 2-undecyl-4R-thiazolidinecarboxylic acid | 298186-80-8 | ≥98.0% | 50MG
2-undecyl-4R-thiazolidinecarboxylic acid | 298186-80-8 | ≥98.0% | 50MG
Apexbio Technology LLC Cy3 hydrazide (non-sulfonated) 50mg
Cy3 hydrazide (non-sulfonated) is an amine-reactive fluorescent dye with excitation and emission maxima around 550 nm and 570 nm respectively As a hydrazide derivative it specifically interacts with aldehyde or ketone groups introduced onto biomolecules such as oxidized antibodies glycoproteins and oligosaccharides or proteins undergoing carbonylation due to oxidative stress Through covalent linkage formation Cy3 hydrazide fluorescently labels these carbonyl-modified targets facilitating their detection and quantification via fluorescence microscopy electrophoresis or mass spectrometry Its applications include monitoring protein oxidation status glycoconjugates characterization and fluorescent labeling of nucleic acids for biochemical or imaging assays