Thiophenes
Medchemexpress LLC AXKO-0046 dihydrochloride | 99.7% | 448.47 | 1 ML
AXKO-0046 dihydrochloride, an indole derivative, is an uncompetitive and selective inhibitor of Lactate dehydrogenase B (LDHB). It demonstrates LDHB inhibitory activity with an EC50 value of 42 nM and is suitable for research in cancer metabolism.
- Indole derivative
- Uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor
- Demonstrates LDHB inhibitory activity with an EC50 value of 42 nM
- Can be utilized for research in cancer metabolism
![Medchemexpress LLC (βS)-β-amino-4-[(3,4-dichlorophenyl)methoxy]-β-methyl-benzenebutanol | 2748196-63-4 | MFCD00006370 | 97.0% | 354.27 g·mol^-1 | C18H21Cl2NO2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238235.png-250.jpg)
Medchemexpress LLC (βS)-β-amino-4-[(3,4-dichlorophenyl)methoxy]-β-methyl-benzenebutanol | 2748196-63-4 | MFCD00006370 | 97.0% | 354.27 g·mol^-1 | C18H21Cl2NO2 | 10MG
P053 is a selective, non-competitive inhibitor of ceramide synthase 1 (CerS1) used in biochemical and cellular research to probe ceramide metabolism, mitochondrial fatty acid oxidation, and adiposity regulation. Reported IC50 is approximately 0.5 μM. The compound is supplied as a white to off-white solid at high purity for in vitro research use.
Medchemexpress LLC 2-Chloro-5-thiophenecarboxaldehyde | 7283-96-7 | 146.59 | 10 G
2-Chloro-5-thiophenecarboxaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Used as a biological material or organic compound for life science related research
TARGETMOL CHEMICALS INC Amthamine 2HCl 1MG
Also available in 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes.5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, including fragile X syndrome, autism spectrum disorders, and addiction. Purity 95%
eMolecules 2-Bromo-4-methylthiophene | 53119-60-1 | MFCD12033287 | 1g
Combi-Blocks | 2-Bromo-4-methylthiophene | 1g | 296398169 | YF-2046 | 95.000 | 53119-60-1 | MFCD12033287 | 177.060 | C5H5BrS
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![eMolecules 5-Chlorobenzo[b]thiophene-3-acetic acid | 17266-30-7 | MFCD00052308 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502185138.JPG-250.jpg)
eMolecules 5-Chlorobenzo[b]thiophene-3-acetic acid | 17266-30-7 | MFCD00052308 | 1g
Combi-Blocks | 5-Chlorobenzo[b]thiophene-3-acetic acid | 1g | 448006966 | QC-0780 | 97.000 | 17266-30-7 | MFCD00052308 | 226.670 | C10H7ClO2S
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![Accela Chembio Inc 2-amino-4 | 5 | 6 | 7-tetrahydrobenzo[b]thiophene-3-carboxamide | 5g | 4815-28-5 | MFCD00111277 | 97+% | Shelf Life: 1800 Days | Light Sensitive/+4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00116475-SY006711-5G.PNG-250.jpg)
Accela Chembio Inc 2-amino-4 | 5 | 6 | 7-tetrahydrobenzo[b]thiophene-3-carboxamide | 5g | 4815-28-5 | MFCD00111277 | 97+% | Shelf Life: 1800 Days | Light Sensitive/+4
2-amino-4 | 5 | 6 | 7-tetrahydrobenzo[b]thiophene-3-carboxamide | 5g | 4815-28-5 | MFCD00111277 | 97+% | Shelf Life: 1800 Days | Light Sensitive/+4
eMolecules 13138-70-0 | Ambeed | 4-Nitrothiophene-2-carboxylic acid | 100mg | 598441848 | A131336 | MFCD07787605 | 173.14 | C5H3NO4S
ChemScene | 5-Bromo-N6-dimethylpyridin-2-amine | 100mg | 712839000 | CS-0380665 | 155789-98-3 | MFCD21784562 | 201.067 | C7H9BrN2
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Apexbio Technology LLC 4-Methylhistamine dihydrochloride 36376-47-3 1mg
4-Methylhistamine dihydrochloride (CAS 36376-47-3) is a selective agonist for the histamine H4 receptor (H4R) displaying a pEC50 of 7 4 0 1 at human H4R It exhibits over 100-fold selectivity for H4R relative to H3R and H2R and over 100 000-fold compared to H1R While affinity for human H4R is moderate it binds rat and mouse H4R with higher affinity (Ki values of 73 nM and 55 nM respectively) In in vivo models 4-Methylhistamine dihydrochloride modulates inflammatory signaling elevating TNF- and NF- B expression via JAK/STAT pathways in response to LPS-induced joint inflammation It serves as a valuable tool in studies of H4R-mediated immune regulation and inflammatory mechanisms
Apexbio Technology LLC Quinacrine 2HCl 69-05-6 10mM (in 1mL H2O)
Quinacrine 2HCl (69-05-6) is an orally active small-molecule inhibitor targeting the NF- B signaling pathway It is designed to inhibit the NF- B cascade thereby downregulating pro-survival gene expression and promoting apoptotic pathways in tumor cells Quinacrine 2HCl exerts its biological activity primarily through inhibition of NF- B and activation of the p53-dependent apoptotic pathway In in vitro studies Quinacrine 2HCl demonstrates growth inhibition of multiple cancer cell lines with reported IC50 values generally in the low micromolar range depending on the specific cell model and experimental context Based on these pharmacological properties Quinacrine 2HCl holds research potential in investigating apoptosis regulatory mechanisms NF- B pathway involvement in cancer biology and preclinical evaluation of potential anticancer therapies
Medchemexpress LLC HY-11083 5mg Medchemexpress, GW-803430 CAS:515141-51-2 Purity:>98%
Medchemexpress, HY-11083 5mg GW-803430 CAS:515141-51-2 GW-803430 (GW-3430) is a potent and selective melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pIC50 of 9.3. GW-803430 is orally active in an animal model of obesity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.