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Filtered Search Results
Aobchem Methyl 3-amino-7-fluorobenzo[b]thiophene-2-carboxylate | ≥97% | CAS 2090172-47-5 | C10H8FNO2S | 1g
Methyl 3-amino-7-fluorobenzo[b]thiophene-2-carboxylate | ≥97% | CAS 2090172-47-5 | C10H8FNO2S | 1g
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Aobchem 5-Bromo-2-chloro-4-fluorobenzonitrile | ≥97% | CAS 1892285-40-3 | C7H2BrClFN | 500mg
5-Bromo-2-chloro-4-fluorobenzonitrile | ≥97% | CAS 1892285-40-3 | C7H2BrClFN | 500mg
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Medchemexpress LLC N-(3-(4-(((2-aminoethyl)(methyl)amino)methyl)-1H-pyrrol-3-yl)-phenyl)acrylamide | 2702280-86-0 | 98.0% | C17H22N4O | 10MG
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MS117 is a first-in-class, cell-active irreversible covalent inhibitor of protein arginine methyltransferase 6 (PRMT6). It inhibits PRMT6 with high biochemical potency and engages the enzyme covalently via an acrylamide Michael acceptor that modifies Cys50, showing both time-dependent irreversible inhibition and cellular activity.
- Irreversible covalent mechanism targeting Cys50.
- Potent biochemical inhibition of PRMT6 (IC50 ≈ 18 nM).
- Demonstrated cellular activity in histone methylation assays.
- Selective profile versus many other methyltransferases at relevant concentrations.
- Available as solid and as DMSO solution to support assay workflows.
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eMolecules 527-72-0 | 2-Thiophenecarboxylic acid | Oakwood Chemical128.150 | C5H4O2S | 97.000 | OC(=O)c1cccs1 | 1g | 537664135
2-Thiophenecarboxylic acid | Oakwood Chemical | 527-72-0128.150 | C5H4O2S | 97.000 | OC(=O)c1cccs1 | 1g | 537664135
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Medchemexpress LLC Anatabine dicitrate | 2741481-51-4 | MFCD32690113 | 99.0% | 544.46 | C22H28N2O14 | 10 MG
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Anatabine dicitrate is a tobacco-derived alkaloid research reagent that functions as a potent α4β2 nicotinic acetylcholine receptor agonist and an inhibitor of NF-κB signaling. It can cross the blood-brain barrier and has been used in preclinical studies to reduce amyloid-β production and modulate neuroinflammatory pathways.
- Potent α4β2 nAChR agonist and NF-κB inhibitor.
- Demonstrates ability to lower amyloid-β production in models.
- Can cross the blood-brain barrier.
- High purity (approximately 99.0%).
- Solid, white to off-white appearance.
- Molecular weight 544.46; formula C22H28N2O14.
- Available in small research pack sizes such as 10 MG.
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Aobchem AOBCHEM
5000905955 4-BROMO-3-ETHOXY-2-FLUOROBENZO
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Aobchem AOBCHEM
5000907245 TERT-BUTYL BENZO B THIOPHENE-2
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Aobchem AOBCHEM
5000903383 5-FLUOROBENZO D 1 3 DIOXOLE 1
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Aobchem AOBCHEM
5001008791 1 3-DIBROMO-2- DIETHOXYMETHYL
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Aobchem AOBCHEM
5001049892 ETHYL 5-OCTYLTHIOPHENE-2-CARBO
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Aobchem AOBCHEM
5001053144 3 6-DIBROMO-2-HYDROXYBENZALDEH
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Aobchem AOBCHEM
5001055381 2 3-DIBROMO-6-CHLOROISONICOTIN
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Aobchem AOBCHEM
5001055522 2 3 5-TRIBROMO-4-METHYLTHIOPHE
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Aobchem AOBCHEM
5001060513 3 5-DIBROMO-4-METHYLBENZALDEHY
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Aobchem Ethyl 5-butylthiophene-2-carboxylate | ≥97% | CAS 2432848-93-4 | C11H16O2S | 250mg
Ethyl 5-butylthiophene-2-carboxylate | ≥97% | CAS 2432848-93-4 | C11H16O2S | 250mg
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