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Medchemexpress LLC 8-(((2r,5r)-5-amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(3-fluoropyridin-2-yl)phenyl)-2-(methylami | 2750707-05-0 | 98.8% | C24H22ClFN6O3 | 10MG
MRIA9 is an ATP-competitive chemical probe that inhibits salt-inducible kinases (SIK1/2/3) and p21-activated kinases (PAK2/3), used in biochemical and cellular studies of SIK/PAK signaling. Reported in vitro IC50 values are 516 nM (SIK1), 180 nM (SIK2), and 127 nM (SIK3). The compound is supplied as a high-purity solid for research use.
