Aralkylamines
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Medchemexpress LLC Chloropyramine hydrochloride | 6170-42-9 | 99.6% | 1 ML
Chloropyramine hydrochloride is a histamine receptor H1 antagonist that also inhibits the biochemical function of VEGFR-3 and FAK. It is intended for research use only and not for patient use. In vitro studies have shown that it causes a significant reduction in the viability of various human cancer cell lines and induces apoptosis in breast cancer cells overexpressing VEGFR-3. In vivo, it has been observed to dramatically reduce tumor growth in model systems, with a low-dose combination with doxorubicin showing a prolonged anti-tumor effect.
- Histamine receptor H1 antagonist
- Inhibits biochemical function of VEGFR-3 and FAK
- Demonstrates cytotoxicity against various human cancer cell lines in vitro
- Induces apoptosis in VEGFR-3 overexpressing breast cancer cells
- Reduces tumor growth in vivo
- Enhanced anti-tumor effect when combined with doxorubicin
