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Organic compounds that contain a carbodiimide functional group; this functional group consists of a carbon atom bonded to two nitrogen atoms via double bonds in the following structure: RN=C=NR. They are exclusively synthetic.
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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NCH 51 is a histone deacetylase (HDAC) inhibitor targeting the removal of acetyl groups from -N-acetylated lysine residues in histone proteins thus modulating gene transcription through chromatin remodeling Experimental data indicate that NCH 51 inhibits proliferation of multiple cancer cell lines including NCI-H460 MDA-MB-231 and HCT-116 with reported EC50 values ranging between 1 1 and 9 5 M Additionally NCH 51 induces apoptosis in lymphoid cell lines through increased caspase activation and reactive oxygen species (ROS) accumulation In HIV-1 latency models NCH 51 enhances histone acetylation and recruits transcription factors to the HIV-1 promoter thereby activating latent viral gene expression
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More