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Carboximidamides

Organic compounds that contain a carbon atom bonded to one nitrogen atoms via a singles bond, and one nitrogen atom via double bond in the following formula: RC(NR)NR2, where R can be hydrogen atoms or any functional group.

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Medchemexpress LLC DNA antisense oligonucleotide (Tofersen) with 2'-O-(2-methoxyethyl) modifications | 2088232-70-4 | 95.5% | 7128.00 | C230H317N72O123P19S15 | 5 MG
SDP

Tofersen is an antisense oligonucleotide that reduces synthesis of superoxide dismutase 1 (SOD1) protein via RNase H-dependent degradation of SOD1 mRNA. It is supplied as a purified, sequence-modified oligonucleotide for laboratory research, primarily in studies related to amyotrophic lateral sclerosis (ALS).

  • Antisense mechanism mediating RNase H-dependent degradation of SOD1 mRNA.
  • Suitable for ALS-related research applications.
  • Provided as a purified oligonucleotide with documented purity and molecular weight.
  • Sequence modified with 2'-O-(2-methoxyethyl) groups for increased stability.
  • Available in small-mass quantities appropriate for experimental use.
  • Certificate of analysis available for batch verification.

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