Guanidines
Apexbio Technology LLC Metformin HCl 1115-70-4 10g
Metformin hydrochloride (Metformin HCl CAS 1115-70-4) is a widely studied small molecule employed in biomedical research primarily for investigating glucose metabolism and type 2 diabetes mechanisms It acts through selective inhibition of hepatic gluconeogenesis without directly increasing insulin secretion The molecular targets include activation of AMP-activated protein kinase (AMPK) subsequently suppressing acetyl-CoA carboxylase (ACC) activity attenuating lipid biosynthesis and promoting fatty acid oxidation Additionally metformin inhibits mitochondrial glycerophosphate dehydrogenase (mGPD) changing cellular redox status and reducing lactate-driven gluconeogenesis pathways Key research applications of Metformin HCl include studies on glucose homeostasis metabolic disorders and AMPK signaling cascades
eMolecules 657-24-9 | Metformin | Combi-Blocks, Inc. | MFCD00242652 | 129.167 | C4H11N5 | 98.000 | CN(C)C(=N)NC(N)=N | 10g | 603134453
Metformin | Combi-Blocks, Inc. | 657-24-9 | MFCD00242652 | 129.167 | C4H11N5 | 98.000 | CN(C)C(=N)NC(N)=N | 10g | 603134453
Sigma Aldrich Fine Chemicals Biosciences Metformin hydrochloride | 1115-70-4 | MFCD00012582 | 200 mg
Metformin hydrochloride | Mol Wt: 165.62 | 1115-70-4 | MFCD00012582 | 200 mg
Selleck Chemical LLC Metformin HCl S1950-1g
Metformin HCl (1 1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis) Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
U.S. Pharmacopeia Metformin hydrochloride, 1115-70-4, MFCD00012582, 200 mg
Linear Formula: NH2C(=NH)NHC(=NH)N(CH3)2 · HCl, Molecular Weight: 165.62, MP: 223-226 °C, Synonym: 1,1-Dimethylbiguanide hydrochloride, Metformin.
Med Vet International Metformin Hcl (Generic Glucophage) Tablets 1000mg, 100 Tablets
Metformin HCl (Generic Glucophage) Tablets 1000mg, 100 tablets