Isocyanates
eMolecules 2-Amino-1-(2-naphthyl)-1-ethanone hydrochloride | 38061-36-8 | MFCD08056659 | 500mg
Matrix Scientific | 2-Amino-1-(2-naphthyl)-1-ethanone hydrochloride | 500mg | 389720944 | 45302 | 95.000 | 38061-36-8 | MFCD08056659 | 221.680 | C12H12ClNO
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Cayman Chemical LBiopterin Fatty Acids and Der
An intermediate for tetrahydro-L-biopterin; oxidized form of BH4, a NOS cofactor; toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs); rarely found under physiological conditions except in the epidermis of patients with Vitiligo
Cayman Chemical 16 17EpDPA Fatty Acids and Der
A DHA metabolite derived via epoxidation of the 16,17-double bond; epoxygenase metabolites of DHA have been detected in a mouse model of inflammation
Cayman Chemical Zeaxanthin Fatty Acids and Der
A carotenoid with diverse biological activities; decreases immobility time in the forced swim test and reduces hippocampal levels of IL-6, IL-1β, and TNF-α in a rat model of STZ-induced diabetes at 50 mg/kg; reduces albuminuria, serum levels of urea nitrogen and MDA, and kidney damage in a rat model of STZ-induced diabetic nephropathy; high dietary intake of zeaxanthin is positively correlated with reduced risk of advanced neovascular age-related macular degeneration in humans
Cayman Chemical Lipoxin A5 Fatty Acids and Der
A 5-series LO derived from EPA; contracts pulmonary parenchymal strips from guinea pig with similar potency to that of LXA4 and LXB4, yet does not exert the vasodilatory effects on aortic smooth muscle exhibited by LXA4 and LXB4
Cayman Chemical 14 15EETSI Fatty Acids and Der
A metabolically stable methyl sulfonamide analog of 14(15)-EET; equipotent to 14(15)-EET in vascular agonist activity
Medchemexpress LLC Hexamethylene bisace | 3073-59-4 | 99.6% | 200.28 g/mol | C10H20N2O2 | 200MG
Hexamethylene bisacetamide (HMBA) is a research reagent used to induce cell differentiation and to study apoptosis and related signaling pathways. It is supplied as a solid and as DMSO solutions for in vitro laboratory applications, and is offered in multiple pack sizes for different experimental scales.
- Induces cell differentiation in multiple cell lines.
- Used to study apoptosis and signaling pathways.
- Supplied as a solid and as DMSO solutions for flexible use.
- Available in multiple pack sizes to suit experimental scale.
- High purity (99.6%) suitable for analytical and research use.
Medchemexpress LLC XL-3158 | 3117797-77-7 | 99.55% | 690.61 | 50 MG
XL-3158 is a selective, cross-species Cyclic GMP-AMP synthase (cGAS) inhibitor. It has an IC50 of 11.1 μM for human cGAS and 2.19 μM for mouse cGAS. This compound simultaneously occupies allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation, which attenuates cGAS-DNA interactions. XL-3158 inhibits cGAS by targeting phase separation, efficiently penetrating cells by inhibiting aggregate formation and reducing the local concentration of cGAS within cells. It is suitable for studying cGAS-dependent inflammatory diseases.
- Selective and cross-species cGAS inhibitor.
- Inhibits cGAS by targeting phase separation.
- Efficiently penetrates cells by inhibiting aggregate formation.
- Reduces local concentration of cGAS within cells.
- Can be used for the study of cGAS-dependent inflammatory diseases.
Cayman Chemical 11 12EpETE Fatty Acids and Der
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined
Cayman Chemical Quinestrol Fatty Acids and Der
A synthetic estrogen; effective in hormone replacement therapy
Medchemexpress LLC 5-(N,N-Hexamethylene)-amiloride | 1428-95-1 | 99.1% | 1 ML
5-(N,N-Hexamethylene)-amiloride, also known as Hexamethylene amiloride (HMA), is a potent Na+/H+ exchanger inhibitor derived from amiloride. It effectively decreases intracellular pH (pHi) and has been shown to induce apoptosis in leukemic cells. This compound also acts as an inhibitor of the HIV-1 Vpu virus ion channel and inhibits the replication of mouse hepatitis virus (MHV) and human coronavirus 229E (HCoV229E) in cultured L929 cells.
- Potent Na+/H+ exchanger inhibitor
- Decreases intracellular pH (pHi)
- Induces apoptosis in leukemic cells
- Inhibits HIV-1 Vpu virus ion channel
- Inhibits replication of mouse hepatitis virus (MHV) and human coronavirus 229E (HCoV229E)
- Inhibits human cardiac ion channels hERG, Nav1.5, and Cav1.2
- Exhibits microsomal and mouse plasma stability
- Displays Caco-2 cell permeability
Innovative Research Inc Fngs-Der Rbncls T1 Anml Fr Pur
Fungus-Derived Ribonuclease T1 Animal Free Purified 100ku - Fungus-Derived Ribonuclease T1 Animal Free Purified from Innovative Research has been prepared as a highly purified, microbial (non-mammalian) RNase prepared with non-animal components. This product is a non-mammalian endoribonuclease, specifically for the cleavage of RNA (deaminated RNA) between guanosine 3AE-phosphate residues (or inosine 3AE-phosphate) and the 5AE-OH residues of adjacent nucleotides with the formation of the corresponding intermediate 2AE, 3AE-cyclic phosphates. It cleaves single-stranded RNA releasing oligonucleotides from the guanosine 3AE-phosphate termini. This product has multiple applications in molecular cloning and DNA sequencing. RNase T1 is inhibited by Ag+, Zn2+, Cu2+, and Hg2+ at 1 X mM. The stimulatory effects of both histidine and EDTA are attributed to chelation of contaminating inhibitor cations.