Isocyanates
Cayman Chemical Zeaxanthin Fatty Acids and Der
A carotenoid with diverse biological activities; decreases immobility time in the forced swim test and reduces hippocampal levels of IL-6, IL-1β, and TNF-α in a rat model of STZ-induced diabetes at 50 mg/kg; reduces albuminuria, serum levels of urea nitrogen and MDA, and kidney damage in a rat model of STZ-induced diabetic nephropathy; high dietary intake of zeaxanthin is positively correlated with reduced risk of advanced neovascular age-related macular degeneration in humans
Cayman Chemical Quinestrol Fatty Acids and Der
A synthetic estrogen; effective in hormone replacement therapy
Cayman Chemical 16 17EpDPA Fatty Acids and Der
A DHA metabolite derived via epoxidation of the 16,17-double bond; epoxygenase metabolites of DHA have been detected in a mouse model of inflammation
Cayman Chemical 11 12EpETE Fatty Acids and Der
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined
Cayman Chemical LBiopterin Fatty Acids and Der
An intermediate for tetrahydro-L-biopterin; oxidized form of BH4, a NOS cofactor; toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs); rarely found under physiological conditions except in the epidermis of patients with Vitiligo
Cayman Chemical 19 20EpDPA Fatty Acids and Der
An epoxide metabolite of DHA; formed from DHA by various CYP isoforms; suppresses hCLS formation and liver fibrosis in wild-type mice in a model of NASH at 100 ng/animal, i.p., intraplantar administration induces acute mechanical hyperalgesia in mice
Cayman Chemical 14 15EETSI Fatty Acids and Der
A metabolically stable methyl sulfonamide analog of 14(15)-EET; equipotent to 14(15)-EET in vascular agonist activity
Cayman Chemical 19 20EpDPA Fatty Acids and Der
An epoxide metabolite of DHA; formed from DHA by various CYP isoforms; suppresses hCLS formation and liver fibrosis in wild-type mice in a model of NASH at 100 ng/animal, i.p., intraplantar administration induces acute mechanical hyperalgesia in mice
Cayman Chemical Quinestrol Fatty Acids and Der
A synthetic estrogen; effective in hormone replacement therapy
Cayman Chemical 14 15EpEDE Fatty Acids and Der
An EpEDE acid formed from DGLA, either by a strong oxidizing agent or by cytochrome P450 epoxygenases; biological properties are poorly understood
Cayman Chemical LBiopterin Fatty Acids and Der
An intermediate for tetrahydro-L-biopterin; oxidized form of BH4, a NOS cofactor; toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs); rarely found under physiological conditions except in the epidermis of patients with Vitiligo
Cayman Chemical LBiopterin Fatty Acids and Der
An intermediate for tetrahydro-L-biopterin; oxidized form of BH4, a NOS cofactor; toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs); rarely found under physiological conditions except in the epidermis of patients with Vitiligo
Cayman Chemical Quinestrol Fatty Acids and Der
A synthetic estrogen; effective in hormone replacement therapy
Cayman Chemical Lipoxin A5 Fatty Acids and Der
A 5-series LO derived from EPA; contracts pulmonary parenchymal strips from guinea pig with similar potency to that of LXA4 and LXB4, yet does not exert the vasodilatory effects on aortic smooth muscle exhibited by LXA4 and LXB4
Cayman Chemical 11 12EpETE Fatty Acids and Der
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined