Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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1,861 – 1,875 of 4,996 results

1,861

Medchemexpress LLC Arg1-in-1 (hydrochloride) | 00-00-0 | 90.0% | 292.57 g·mol⁻1 | C11H22BClN2O4 | 5 MG

ARG1-IN-1 hydrochloride is a small-molecule inhibitor of human arginase 1 with a reported IC50 of 29 nM. It is intended for research use in biochemical and cellular studies to probe arginase-related pathways. The hydrochloride form improves handling and aqueous compatibility for assay preparation.

Potent arginase 1 inhibition (IC50 29 nM).
Suitable for biochemical and cellular assays.
Provided as a 5 mg quantity for small-scale research use.
Molecular weight 292.57 g·mol⁻1; formula C11H22BClN2O4.
Purity typically 90.0% as reported on the certificate of analysis.
Store at -20°C under nitrogen and protect from moisture; in solvent store at -80°C for long-term.

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1,862

Medchemexpress LLC Pargyline hydrochloride | 306-07-0 | MFCD00012492 | 99.91% | C11H14ClN | 100 MG

Pargyline hydrochloride is an irreversible monoamine oxidase (MAO) inhibitor with antihypertensive and anticancer activities. It functions as a click chemistry reagent, containing an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Irreversible monoamine oxidase (MAO) inhibitor
Exhibits antihypertensive activities
Demonstrates anticancer activities
Functions as a click chemistry reagent
Contains an alkyne group for CuAAc reactions

Pricing & Availability

1,863

Medchemexpress LLC VTP-27999 Hydrochloride | 1264191-73-2 | 98.18% | C26H42Cl2N4O5 | 100 MG

VTP-27999 Hcl is an alkyl amine Renin inhibitor useful for Hypertension and End-Organ Diseases, targeting Renin with an IC50 value.

Alkyl amine Renin inhibitor
Useful for hypertension and end-organ diseases
Targets renin (IC50 value)

Pricing & Availability

1,864

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG

Ansofaxine hydrochloride is a triple reuptake inhibitor designed to inhibit serotonin, dopamine, and norepinephrine reuptake. It demonstrates IC50 values of 723 nM, 491 nM, and 763 nM for these reuptake processes, respectively. This compound is intended for research use only.

Triple reuptake inhibitor
Inhibits serotonin, dopamine, and norepinephrine reuptake
Intended for research use only
Appears as a solid
Color ranges from white to off-white
Recommended storage for solid is 4°C, sealed and away from moisture
For solutions, store at -80°C for up to 6 months, or -20°C for 1 month

Pricing & Availability

1,865

Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | MFCD00899568 | 99.5% | 458.08 g/mol | C27H40ClN3O | 1 ML

Nevanimibe hydrochloride is the hydrochloride salt of nevanimibe, a selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor supplied as a 10 mM solution in DMSO (1 mL) for in vitro research use.

Selective ACAT1 inhibitor with low-nanomolar activity
Supplied as a ready-to-use 10 mM solution in DMSO
High purity (~99.5%) suitable for biochemical and cell-based assays
Molecular weight 458.08 g/mol aids solution preparation calculations
Available in solid and solution formats for flexibility in workflows

Pricing & Availability

1,866

Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | 98.63% | 369.89 | 1 ML

VU0357017 hydrochloride is a potent, selective, and brain-penetrant allosteric agonist of the M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. It is highly selective for M1, showing no activity at M2-M5 receptors up to 30 μM. This compound is used in research for conditions such as Alzheimer's disease and schizophrenia.

Potent and selective M1 muscarinic acetylcholine receptor agonist.
Exhibits brain penetrant properties.
Highly selective for M1 over M2-M5 receptors.
Used for the research of Alzheimer's disease and schizophrenia.

Pricing & Availability

1,867

Medchemexpress LLC Thialysine hydrochloride | 4099-35-8 | 98.0% | 1 G

Thialysine hydrochloride is the hydrochloride salt of thialysine, a cysteine-derived amino acid analog used for biochemical and protein-synthesis research.

Purity 98.0%
Molecular weight 200.69 g/mol
Chemical formula C5H13ClN2O2S
Appearance white to off-white solid
Available pack sizes include 250 MG, 500 MG, 1 G, 5 G, 10 G
Store sealed at -20°C; in solvent: -80°C (6 months), -20°C (1 month)
Datasheet, COA, and SDS available

Pricing & Availability

1,868

Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.9% | 338.85 | 10 MG

AkaLumine hydrochloride is an analogue of D-luciferin that emits near-infrared (NIR) light (λmax=677 nm) when reacting with native firefly luciferase (Fluc) protein. It offers high tissue-penetration and increased detection sensitivity from deep-tissue targets.

Near-infrared (NIR) emission allows for high tissue-penetration.
Enhances detection sensitivity from deep-tissue targets.
Functions similarly to D-luciferin with a specified Km for recombinant firefly luciferase.
Can be used to detect Akaluc expression in vitro and for subcutaneous/orthotopic tumor mouse imaging in vivo.

Pricing & Availability

1,869

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It significantly inhibits tumor growth in mouse xenograft models without detectable toxicity and regulates the production of γ-H2AX in cancer cells. This compound has shown growth suppressive effects in human cancer cell line derived xenograft models.

Potent SUV39H2 inhibitor
Inhibits tumor growth in mouse xenograft models
Regulates production of γ-H2AX in cancer cells
Shows significant inhibition of tumor growth without detectable toxicity
Inhibits A549 cell growth with an IC50 of 0.67 μM
Exhibits growth suppressive effects in human cancer cell line derived xenograft models

Pricing & Availability

1,870

Medchemexpress LLC EPZ020411 hydrochloride | 2070015-25-5 | 98.2% | 50 MG

EPZ020411 hydrochloride is a potent and selective inhibitor of protein arginine methyltransferase 6 (PRMT6) with an IC50 of 10 nM. It exhibits over 10-fold selectivity for PRMT6 compared to PRMT1 and PRMT8. This compound is valuable for cancer research and has demonstrated the ability to decrease H3R2 methylation in A375 cells, as well as reduce neomycin- and cisplatin-induced cell apoptosis, thereby increasing hair cell survival.

Selective inhibitor of PRMT6
IC50 of 10 nM for PRMT6
Over 10-fold selectivity for PRMT6 over PRMT1 and PRMT8
Can be used for cancer research
Decreases H3R2 methylation in A375 cells
Reduces neomycin- and cisplatin-induced cell apoptosis
Increases hair cell survival

Pricing & Availability

1,871

Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG

Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and can be used for research on cardiovascular diseases such as orthostatic hypotension.

Strengthens vascular contraction
Increases p-AMPK and PPARδ expression in C2C12, HL1, and HepG2 cells
Increases Ca2+ in C2C12, HL1, and HepG2 cells
Increases maximal mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
Reduces cellular lipid content in 3T3-L1 cells
Reduces platelet-activating factor (Paf)-induced death in mice
Shows anti-hypotensive effects in orthostatic hypotension rat models
Relieves hypertension in spontaneously hypertensive rat models

Pricing & Availability

1,872

Medchemexpress LLC Iptacopan hydrochloride | 1646321-63-2 | 99.8% | 1 ML

Iptacopan (LNP023) hydrochloride is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. It prevents the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G by exerting a proximal effect in the complement cascade reaction. It can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G).

Effective and orally-active highly selective factor B inhibitor
IC50 value of 10 nM and KD of 7.9 nM
Prevents destruction (hemolysis) of red blood cells in PNH
Prevents damage of renal cells in IgAN and C3G
Used for the study of complement-mediated diseases
Particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)

Pricing & Availability

1,873

Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 50 MG

Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib. It is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2, and 3, with IC50s of 30, 6.5, and 15 nM, respectively. It demonstrates antitumor efficacy.

Selective, orally active inhibitor for VEGFR-1, 2, and 3
Exhibits antitumor efficacy
Inhibits phosphorylation of VEGFR-1, VEGFR-2, and VEGFR-3 with IC50s of 0.16-0.24 nM in vitro
Inhibits VEGF-induced proliferation and migration of HUVECs in vitro
Selectively inhibits VEGF-stimulated phosphorylation of MAPKs in endothelial cells in vitro
Shows antitumor efficacy against breast, colon, hepatic, lung, ovarian, pancreatic, and prostate cancer in athymic mice models in vivo
Reversibly suppresses vascular permeability and angiogenesis in Calu-6 tumor bearing rats in vivo

Pricing & Availability

1,874

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML

Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, independent of androgen receptor status. It also suppresses the transcriptional activity of the androgen receptor, which regulates fatty acid synthesis.

Acts as a cannabinoid receptor type 1 (CB1) agonist
Inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
Suppresses the transcriptional activity of the androgen receptor
Extracted from the bark of pine trees
Appears as a white to off-white solid
Store at -20°C in sealed conditions, away from moisture
For storage in solvent, store at -80°C for 6 months, or -20°C for 1 month in sealed conditions, away from moisture

Pricing & Availability

1,875

Medchemexpress LLC SB-277011 hydrochloride | 215804-67-4 | 99.59% | 475.02 | 50 MG

SB-277011 hydrochloride is a potent and selective dopamine D3 receptor (D3R) antagonist, demonstrating high oral bioavailability and brain penetrance. It exhibits significant selectivity over other dopamine receptors and possesses an excellent pharmacokinetic profile in rats. This compound has been shown to effectively reverse the effects of quinelorane and reduce cocaine self-administration in preclinical studies.

Potent and selective D3 receptor antagonist
High oral bioavailability and brain penetrance
80- to 100-fold selectivity over other dopamine receptors
Excellent pharmacokinetic profile
Reverses quinelorane effects in nucleus accumbens
Reduces intravenous cocaine self-administration
Inhibits basal and cocaine-enhanced locomotion
Appearance: solid, off-white to light yellow

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Alcohols and polyols

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Medchemexpress LLC Arg1-in-1 (hydrochloride) | 00-00-0 | 90.0% | 292.57 g·mol⁻1 | C11H22BClN2O4 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pargyline hydrochloride | 306-07-0 | MFCD00012492 | 99.91% | C11H14ClN | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VTP-27999 Hydrochloride | 1264191-73-2 | 98.18% | C26H42Cl2N4O5 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | MFCD00899568 | 99.5% | 458.08 g/mol | C27H40ClN3O | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | 98.63% | 369.89 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thialysine hydrochloride | 4099-35-8 | 98.0% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.9% | 338.85 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EPZ020411 hydrochloride | 2070015-25-5 | 98.2% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Iptacopan hydrochloride | 1646321-63-2 | 99.8% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-277011 hydrochloride | 215804-67-4 | 99.59% | 475.02 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More