Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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3,841 – 3,855 of 5,327 results

3,841

Medchemexpress LLC Nebivolol hydrochloride | 152520-56-4 | 99.9% | 1 ML

Nebivolol hydrochloride (R 065824) is an orally active beta receptor blocker with high beta(1)-receptor affinity. It possesses direct vasodilator properties and adrenergic blocking characteristics.

Used for research into various diseases
High beta(1)-receptor affinity
Direct vasodilator properties
Adrenergic blocking characteristics
Orally active beta receptor blocker

Pricing & Availability

3,842

Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | MFCD03703482 | 99.8% | 500 MG

Amiloride hydrochloride is a research chemical that acts as an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). It also functions as a blocker of the polycystin-2 (PC2; TRPP2) channel. This compound is intended for research use only.

Inhibits epithelial sodium channel (ENaC).
Inhibits urokinase-type plasminogen activator receptor (uTPA).
Blocks polycystin-2 (PC2; TRPP2) channel.
Selective inhibitor of ENaC with an IC50 ranging from 0.1 to 0.5 μM.
Reverses and prevents increases in collagen deposition in DOCA-salt hypertensive rats.
Delays proteinuria and improves brain and kidney scores in SHRSP rats.
Antagonizes aldosterone actions in cardiovascular and renal tissues.

Pricing & Availability

3,843

Medchemexpress LLC Tiagabine (hydrochloride) | 145821-59-6 | MFCD00892911 | ≥98% | 1 ML

Tiagabine (hydrochloride) is an anticonvulsant agent and a selective inhibitor of the GAT-1 GABA transporter. It potently and selectively inhibits GABA reuptake and demonstrates neuroprotective properties.

Selective inhibitor of GAT-1 GABA transporter
Potently and selectively inhibits GABA reuptake
Exhibits neuroprotective properties
Protects neurons against mutant huntingtin-induced toxicity
Increases viability of SH-SY5Y cells
Inhibits GABA uptake in mouse GAT1 expressed in HEK293 cells

Pricing & Availability

3,844

Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.12% | 100 MG

Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. It is a cardioselective beta-adrenergic receptor blocking agent. It has been shown to diminish anxiety-like behavior during early withdrawal from chronic cocaine administration in rats, and it produces less systemic beta 2- and possibly beta 1-adrenergic receptor blockade than either timolol or levobunolol, potentially making it safer for patients with reactive airway disease.

Selective beta1 adrenergic receptor blocker
Used in research for hypertension and glaucoma
Cardioselective beta-adrenergic receptor blocking agent
Diminishes anxiety-like behavior during withdrawal from chronic cocaine administration in rats
Produces less systemic beta 2- and possibly beta 1-adrenergic receptor blockade

Pricing & Availability

3,845

Medchemexpress LLC Amprolium hydrochloride | 137-88-2 | 98.79% | 250 MG

Amprolium hydrochloride is an anti-parasitic drug that is taken orally and acts as an antagonist to thiamine in intestinal absorption. It is for research use only and not sold to patients.

Acts as an antagonist to thiamine in intestinal absorption
Targets Coccidia
Suitable for in vivo and in vitro applications
For research use only

Pricing & Availability

3,846

Medchemexpress LLC Alfuzosin hydrochloride | 81403-68-1 | 99.7% | 50 MG

Alfuzosin hydrochloride is an orally active, selective and competitive α1-adrenoceptor antagonist. It relaxes the muscles of the prostate and bladder neck, aiding in urination. This compound can be used in the study of benign prostatic hyperplasia (BPH).

Orally active
Selective and competitive α1-adrenoceptor antagonist
Relaxes the muscles of the prostate and bladder neck
Aids in urination
Can be used in the study of benign prostatic hyperplasia (BPH)

Pricing & Availability

3,847

Medchemexpress LLC Nebivolol hydrochloride | 152520-56-4 | MFCD07357273 | 99.9% | 50 MG

Nebivolol hydrochloride is an orally active beta receptor blocker with high beta(1)-receptor affinity. It possesses direct vasodilator properties and adrenergic blocking characteristics. This compound is used for the research of various diseases such as hypertension, coronary artery disease, congestive heart failure, and ischemic heart disease.

Orally active beta receptor blocker
High beta(1)-receptor affinity
Direct vasodilator properties
Adrenergic blocking characteristics
Improves endothelial dysfunction
Stimulates endothelial nitric oxide synthase activity
Antioxidative properties
Inhibits haCSMC and haEC proliferation
Induces moderate apoptosis
Increases NO formation and decreases endothelin-1 secretion

Pricing & Availability

3,848

Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 1 ML

Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels, demonstrating local anesthetic activity by blocking nerve impulse conduction. It also exhibits anti-inflammatory functions by inhibiting NF-κB activation and NLRP3 inflammasome pathways. It is used in the study of dental local anesthesia and inflammatory-related diseases.

Inhibits voltage-gated sodium channels
Exhibits local anesthetic activity
Inhibits NF-κB activation and NLRP3 inflammasome pathways
Reduces inflammatory factors like TNF-α, IL-6, and IL-1β
Ameliorates LPS-induced acute kidney injury in animal models
Can enhance anesthetic effect in zebrafish model

Pricing & Availability

3,849

Medchemexpress LLC Amprolium (hydrochloride) | 137-88-2 | 98.8% | 1 ML

Amprolium hydrochloride is provided as a 10 mM solution in 1 mL, with a purity of 98.8%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.

10 mM solution in 1 mL
Purity: 98.8% (HPLC)
Recommended storage: 4°C for sealed solutions, away from moisture
For longer-term storage in solvent: -80°C for 6 months or -20°C for 1 month
Can be shipped at room temperature if shipment duration is less than 2 weeks
Intended for research applications

Pricing & Availability

3,850

Medchemexpress LLC Fendiline (hydrochloride) | 13636-18-5 | 99.8% | 1 ML

Fendiline hydrochloride is a diphenylalkylamine type of antianginal agent that acts as an L-type calcium channel blocker with an IC50 of 17 μM. It is also identified as a selective K-Ras inhibitor, showing no effect on H-Ras and N-Ras. It inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM) and K-Ras signal output. Additionally, Fendiline hydrochloride is a STING agonist and has demonstrated the ability to inhibit the growth of multiple refractory cold tumors. This product is provided as a 10 mM solution in 1 mL of DMSO with a purity of 99.78%.

Acts as an L-type calcium channel blocker
Functions as a selective K-Ras inhibitor
Inhibits K-Ras plasma membrane localization
Suppresses K-Ras signal output
Prevents proliferation of various cancer cell lines
Serves as a STING agonist
Inhibits growth of refractory cold tumors

Pricing & Availability

3,851

Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 5 G

Trazodone hydrochloride is a triazolopyridine derivative that acts as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity by antagonizing α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. It is suitable for various laboratory applications and research.

Exhibits anti-depressant and anti-insomnious activity
Acts as an antagonist against α1- and α2-adrenergic receptors
Antagonizes histamine H1 receptors
Demonstrates minimal anticholinergic effects
Binds to 5-HT1A receptor
Reduces expression of neuroinflammatory markers
Increases mRNA expression of BDNF and CREB

Pricing & Availability

3,852

Medchemexpress LLC 9h-Carbazole-3-methanamine, 9-ethyl-N-methyl-, hydrochloride (1:1) | 1050480-30-2 | 99.3% | 274.79 | 1 ML

PhiKan 083 hydrochloride is a carbazole derivative that binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells.

Slows down its thermal denaturation rate.

Pricing & Availability

3,853

Medchemexpress LLC BMY-14802 hydrochloride | 105565-55-7 | 98.0% | 384.85 | 500 UG

BMY-14802 hydrochloride (BMY-14802-1) is a selective and orally active sigma receptor antagonist with an IC50 of 112 nM. It is also a 5-HT1A and adrenergic α1 receptors agonist. BMY-14802 hydrochloride has antipsychotic effects.

Selective and orally active sigma receptor antagonist.
Acts as a 5-HT1A and adrenergic α1 receptor agonist.
Exhibits antipsychotic effects.

Pricing & Availability

3,854

Medchemexpress LLC SAR407899 hydrochloride | 923262-96-8 | MFCD20485429 | 99.1% | 280.75 g/mol | C14H17ClN2O2 | 10 MG

SAR407899 hydrochloride is a selective, potent, ATP-competitive inhibitor of Rho-associated kinases (ROCK), supplied as a high-purity solid for preclinical biochemical and cellular research. It is used to probe ROCK-mediated signaling, vascular tone, and smooth muscle responses in vitro and in vivo.

Selective ATP-competitive ROCK inhibitor with ROCK-2 IC50 ≈135 nM.
Demonstrates Ki values of 36 nM (human) and 41 nM (rat).
High purity (99.1%) suitable for research applications.
Solid, light yellow to khaki appearance; stable when stored sealed at 4°C.
Applicable to studies of vascular tone, smooth muscle relaxation, and ROCK signaling pathways.

Pricing & Availability

3,855

Medchemexpress LLC Sematilide hydrochloride | 101526-62-9 | MFCD01667315 | 99.3% | 349.88 g·mol⁻1 | C14H24ClN3O3S | 100 MG

Sematilide hydrochloride is a class III antiarrhythmic research compound that selectively blocks the cardiac IKr (hERG) potassium channel. It inhibits the delayed rectifier K+ current in a concentration-dependent manner (reported IC50 ≈ 25 μM) and is supplied as the hydrochloride salt for in vitro electrophysiology and pharmacology studies. Typical purity is 99.33%.

Selective IKr (hERG) channel blocker
Inhibits delayed rectifier K+ current (IC50 ≈ 25 μM)
Intended for in vitro electrophysiology and pharmacology studies
High purity suitable for analytical applications
Available in milligram pack sizes for research use

Pricing & Availability

Alcohols and polyols

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Medchemexpress LLC Nebivolol hydrochloride | 152520-56-4 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | MFCD03703482 | 99.8% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tiagabine (hydrochloride) | 145821-59-6 | MFCD00892911 | ≥98% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.12% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amprolium hydrochloride | 137-88-2 | 98.79% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alfuzosin hydrochloride | 81403-68-1 | 99.7% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nebivolol hydrochloride | 152520-56-4 | MFCD07357273 | 99.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Articaine hydrochloride | 23964-57-0 | 99.4% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amprolium (hydrochloride) | 137-88-2 | 98.8% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fendiline (hydrochloride) | 13636-18-5 | 99.8% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 9h-Carbazole-3-methanamine, 9-ethyl-N-methyl-, hydrochloride (1:1) | 1050480-30-2 | 99.3% | 274.79 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BMY-14802 hydrochloride | 105565-55-7 | 98.0% | 384.85 | 500 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SAR407899 hydrochloride | 923262-96-8 | MFCD20485429 | 99.1% | 280.75 g/mol | C14H17ClN2O2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sematilide hydrochloride | 101526-62-9 | MFCD01667315 | 99.3% | 349.88 g·mol⁻1 | C14H24ClN3O3S | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More