Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,831 – 4,845 of 5,342 results

4,831

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 1 ML

Azasetron hydrochloride (Y-25130 hydrochloride) is a benzamide derivative that functions as a potent and selective 5-HT3 receptor antagonist. It is currently under study for its application in treating chemotherapy-induced nausea and vomiting (CINV).

Potent and selective 5-HT3 receptor antagonist.
Used to study chemotherapy-induced nausea and vomiting (CINV).
Can effectively penetrate the skin and enter systemic circulation.

Pricing & Availability

4,832

Medchemexpress LLC mAChR-IN-1 (hydrochloride) | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 10MM 1ML

mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor antagonist (IC50 17 nM) provided for research use. It is offered as a solid and as a pre-made solution in DMSO, intended for in vitro pharmacology and receptor binding studies.

Potent mAChR antagonist (IC50 17 nM).
High purity: 99.6% (LCMS).
Chemical formula: C23H26ClIN2O2.
Molecular weight: 524.82 g/mol.
Physical appearance: white to off-white solid.
Available as solids (5-100 mg) and 10 mM solution in DMSO, 1 mL.
Supplied for research use only.

Pricing & Availability

4,833

Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 260.72 | C11H17ClN2O3 | 5 MG

Nifenalol hydrochloride is a β-adrenergic receptor antagonist used in cardiac electrophysiology and pharmacology research. The compound is reported to induce early afterdepolarization (EAD) and is used to study arrhythmia and blood pressure-related effects.

Beta-adrenergic receptor antagonist activity
Induces early afterdepolarization useful for arrhythmia studies
Hydrochloride salt form for improved solubility
Molecular formula C11H17ClN2O3
Molecular weight 260.72
Available in small research pack sizes (e.g., 5 mg)
Intended for in vitro and in vivo research applications

Pricing & Availability

4,834

Medchemexpress LLC Indotecan (hydrochloride) | 1228035-68-4 | 99.8% | 514.95 | 25 MG

Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor. It has IC50s of 300, 1200, and 560 nM for P388, HCT116, and MCF-7 cell lines, respectively. This compound prevents the relaxation of supercoiled DNA and can be utilized for research on visceral leishmaniasis.

Potent Topoisomerase I inhibitor.
Effective in preventing relaxation of supercoiled DNA.
Can be used for research on visceral leishmaniasis.

Pricing & Availability

4,835

Medchemexpress LLC CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 100 MG

CP-640186 hydrochloride is an orally active and cell-permeable inhibitor of Acetyl-CoA carboxylase (ACC). It exhibits IC50 values of 53 nM for rat liver ACC1 and 61 nM for rat skeletal muscle ACC2. ACC is a crucial enzyme involved in fatty acid metabolism, responsible for synthesizing malonyl-CoA. This compound also promotes muscle fatty acid oxidation.

Orally active and cell-permeable.
Inhibits Acetyl-CoA carboxylase (ACC).
IC50s: 53 nM for rat liver ACC1, 61 nM for rat skeletal muscle ACC2.
Stimulates muscle fatty acid oxidation.

Pricing & Availability

4,836

Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | 99.9% | 403.90 | 50 MG

Bambuterol hydrochloride is a long-acting beta-adrenoceptor agonist (LABA) that is used to treat asthma; it is also a proagent of terbutaline.

Acts as a long-acting beta-adrenoceptor agonist (LABA)
Used in the treatment of asthma
Functions as a proagent of terbutaline

Pricing & Availability

4,837

Medchemexpress LLC Fadrozole hydrochloride hemihydrate | 176702-70-8 | 99.6% | 268.74 | 25 MG

Fadrozole hydrochloride hemihydrate is an orally active, potent, selective, and nonsteroidal aromatase inhibitor, with an IC50 of 6.4 nM. It inhibits the production of estrogen and progesterone, with IC50 values of 0.03 and 120 μM, respectively. This compound shows prevention of spontaneous tumors and can be used for research on estrogen-dependent diseases and cancer.

Orally active
Potent, selective, and nonsteroidal aromatase inhibitor (IC50 of 6.4 nM)
Inhibits estrogen production (IC50 of 0.03 μM)
Inhibits progesterone production (IC50 of 120 μM)
Prevents spontaneous tumors
Useful for research of estrogen-dependent diseases and cancer

Pricing & Availability

4,838

Medchemexpress LLC 7H-pyrrolo[2,3-d]pyrimidin-4-amine, N-butyl-N-ethyl-2,5,6-trimethyl-7-(trimethylphenyl) hydrochloride | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 50 MG

Antalarmin hydrochloride is a research-grade, non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist supplied as a white to light yellow solid for preclinical research. It is used to study stress-response pathways, CRH/CRF signaling, anxiety-like behavior, and inflammation models. The compound is provided at high purity and supplied in small mg-scale pack sizes suitable for laboratory use.

Non-peptide CRHR1 antagonist used in stress and neuroendocrine research.
High purity for reliable experimental results.
Solid form, easy to weigh and formulate.
Available in mg-scale pack sizes for preclinical studies.
Includes datasheet, certificate of analysis, and safety data sheet documentation.

Pricing & Availability

4,839

Medchemexpress LLC CHK1-IN-4 hydrochloride | 00-00-0 | 480.75 g/mol | C18H19BrClN7O2 | 5 MG

CHK1-IN-4 hydrochloride is the hydrochloride salt of a small-molecule inhibitor of checkpoint kinase 1 (CHK1). It is used in preclinical biochemical and cell-based studies to inhibit CHK1 phosphorylation and evaluate antitumor activity. Supplied as a solid with defined solubility and storage recommendations for research use.

Potent checkpoint kinase 1 (CHK1) inhibitor active in tumor cells.
Hydrochloride salt form for improved solubility and handling.
Solid material; soluble in DMSO at 5 mg/mL with ultrasonic and warming.
Storage: in solvent -80°C for up to 6 months; sealed -20°C for up to 1 month.
Supplied in small research pack sizes suitable for preclinical studies.

Pricing & Availability

4,840

Medchemexpress LLC Vatinoxan (hydrochloride) | 130466-38-5 | MFCD08056257 | 99.8% | 10 MG

Vatinoxan hydrochloride is the hydrochloride salt of vatinoxan, a peripherally selective α2-adrenergic receptor antagonist supplied as a high-purity solid for research use in pharmacology and in vivo studies.

Peripherally selective α2-adrenergic receptor antagonist for pharmacological studies.
High purity (≈99.8%) suitable for analytical and in vivo use.
Hydrochloride salt supplied as a solid with good stability under recommended storage conditions.
Soluble in DMSO (~10 mg/mL); ultrasonic agitation may be required.
Recommended storage: refrigerated under inert atmosphere; solution stability at -80°C (6 months) or -20°C (1 month).
Available in multiple small research quantities for dosing and formulation studies.

Pricing & Availability

4,841

Medchemexpress LLC Mefuparib hydrochloride | 1449746-00-2 | 98.6% | 334.77 | 5 MG

Mefuparib hydrochloride is an orally active, substrate-competitive, and selective inhibitor of PARP1/2, with IC50 values of 3.2 nM and 1.9 nM respectively. It is known to induce apoptosis and exhibits significant anticancer activity both in vitro and in vivo.

Orally active.
Substrate-competitive and selective PARP1/2 inhibitor.
Induces apoptosis.
Possesses prominent anticancer activity in vitro and in vivo.

Pricing & Availability

4,842

Medchemexpress LLC Ribociclib hydrochloride | 1211443-80-9 | >99.9% | 471.00 | 10 MG

Ribociclib hydrochloride is an ATP-competitive and orally active CDK4/6 inhibitor designed for research use. It effectively crosses the blood-brain barrier and demonstrates potent inhibitory activity against CDK4 and CDK6.

ATP-competitive and orally active CDK4/6 inhibitor
Crosses the blood-brain barrier
IC50 values of 10 nM for CDK4 and 39 nM for CDK6
Over 1,000-fold less potent against the cyclin B/CDK1 complex
Induces cell-cycle arrest in G0/G1 phase
Significantly delays tumor growth in neuroblastoma xenografts

Pricing & Availability

4,843

Medchemexpress LLC PRT062607 Hydrochloride | 1370261-97-4 | 98.07% | 429.91 | 50 MG

PRT062607 Hydrochloride is an orally available Syk inhibitor that effectively inhibits inflammation and induces apoptosis. It demonstrates potent antitumor activity in tumor xenograft mouse models. This compound inhibits phosphorylation of ERK, AKT, and SYK in Ramos cells, and BLNK Tyr84 phosphorylation in a concentration-dependent manner.

Inhibits B cell antigen receptor-mediated B cell signaling and activation
Inhibits Fc receptor 1-mediated induced basophil degranulation
Produces dose-dependent anti-inflammatory activity in rodent models of rheumatoid arthritis
Prevents BCR-induced splenomegaly in mice
Prevents Ramos tumor formation in mouse xenograft models
Significantly inhibits NHL tumor growth in xenograft models

Pricing & Availability

4,844

Research Products International Corp Ninhydrin Reagent 10 G

Ninhydrin Reagent, 10 Grams

Pricing & Availability

4,845

Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 99.7% | 362.30 | 25 MG

Clemizole hydrochloride is an H1 histamine receptor antagonist that has been shown to inhibit HCV replication. It is also an inhibitor of the TRPC5 channel. It effectively blocks TRPC5 currents and Ca2+ entry in the low micromolar range.

IC50 for RNA binding by NS4B is 24 nM.
EC50 for viral replication is 8 μM.
Inhibits HCV RNA replication in cell culture by suppressing NS4B's RNA binding, with minimal toxicity to the host cell.
Effectively blocks TRPC5 currents and Ca2+ entry in the low micromolar range (IC50=1.0-1.3 μM).
Exhibits selectivity for TRPC5 over TRPC4β, TRPC3, and TRPC6.

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Alcohols and polyols

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Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC mAChR-IN-1 (hydrochloride) | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 260.72 | C11H17ClN2O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Indotecan (hydrochloride) | 1228035-68-4 | 99.8% | 514.95 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | 99.9% | 403.90 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fadrozole hydrochloride hemihydrate | 176702-70-8 | 99.6% | 268.74 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CHK1-IN-4 hydrochloride | 00-00-0 | 480.75 g/mol | C18H19BrClN7O2 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Vatinoxan (hydrochloride) | 130466-38-5 | MFCD08056257 | 99.8% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mefuparib hydrochloride | 1449746-00-2 | 98.6% | 334.77 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ribociclib hydrochloride | 1211443-80-9 | >99.9% | 471.00 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PRT062607 Hydrochloride | 1370261-97-4 | 98.07% | 429.91 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Ninhydrin Reagent 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 99.7% | 362.30 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More