Alcohols and polyols
- (1)
- (55)
- (350)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (29)
- (14)
- (3)
- (1)
- (1)
- (10)
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- (2)
- (2)
- (1)
- (1)
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- (1)
- (1)
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- (30)
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- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (116)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (1)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
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- (1)
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- (1)
- (1)
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- (1)
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- (1)
- (1)
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- (3)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (2)
- (1)
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- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
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- (1)
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- (1)
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- (2)
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- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (1)
- (9)
- (1)
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- (3)
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- (1)
- (1)
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- (2)
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- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
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- (7)
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- (15)
- (2)
- (1)
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- (1)
- (2)
- (1)
- (1)
- (1)
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- (1)
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- (2)
- (1)
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- (2)
- (2)
- (1)
- (1)
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- (1)
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- (3)
- (2)
- (7)
- (1)
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- (16)
- (1)
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- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (82)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
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- (1)
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- (16)
- (1)
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- (21)
- (2)
- (2)
- (2)
- (1)
- (67)
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- (2)
- (7)
- (4)
- (86)
- (1)
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- (72)
- (3)
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- (2)
- (2)
- (21)
- (281)
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- (1)
- (6)
- (280)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (733)
- (11)
- (3)
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- (2)
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- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
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- (3)
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- (2)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (12)
- (2)
- (10)
- (2)
- (1)
- (12)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 10 G
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Trazodone hydrochloride (AF-1161) is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). It has antidepressant and anti-insomnious activity and exerts antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.
- Serotonin receptor antagonist and reuptake inhibitor
- Exhibits antidepressant and anti-insomnious activity
- Antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors
- Minimal anticholinergic effects
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Terazosin hydrochloride | 63074-08-8 | 99.9% | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and opening the bladder. It has potential for the treatment of benign prostatic hyperplasia (BPH) and high blood pressure.
- Relaxes blood vessels
- Opens the bladder
- Potential for treatment of benign prostatic hyperplasia (BPH)
- Potential for treatment of high blood pressure
- For research use only
- Solid appearance
- White to off-white color
- Purity: 99.9%
- Molecular weight: 423.89
- Molecular formula: C19H26ClN5O4
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.1% | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Betaxolol hydrochloride is a selective beta1 adrenergic receptor blocker, useful for research into hypertension and glaucoma. It acts as a cardioselective beta-adrenergic receptor blocking agent, potentially safer for patients with reactive airway disease due to reduced systemic beta 2- and beta 1-adrenergic receptor blockade compared to other agents. In vivo studies show it can attenuate anxiety-like behavior during early withdrawal from chronic cocaine administration in rats.
- Selective beta1 adrenergic receptor blocker
- Used for research of hypertension and glaucoma
- Cardioselective beta-adrenergic receptor blocking agent
- Attenuates anxiety-like behavior during cocaine withdrawal in rats
- Potentially safer for patients with reactive airway disease
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 500 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Trazodone hydrochloride is a triazolopyridine derivative classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity. The compound exerts antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.
- Serotonin receptor antagonist and reuptake inhibitor (SARI)
- Exhibits anti-depressant and anti-insomnious activities
- Antagonizes α1- and α2-adrenergic receptors and histamine H1 receptors
- Minimal anticholinergic effects
- Binds to 5-HT1A receptor
- Reduces expression of neuroinflammatory markers
- Increases mRNA expression of BDNF and CREB
- Demonstrates neuroprotective effects
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Medchemexpress LLC PhiKan 083 hydrochloride | 1050480-30-2 | 99.27% | 274.79 | 25 MG
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PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells.
- Binds to the surface cavity and stabilizes Y220C (a p53 mutant)
- Kd of 167 μM (p53-Y220C)
- Relative binding affinity (Kd) of 150 μM in Ln229 cells
- Slows down its thermal denaturation rate
- Reduces the cell viability of engineered variants of Ln229 cells (125 μM, 48 hours)
- Enhances pro-apoptotic activity in all variants of Ln229 cells (p53wt, p53Y220C, p53G245S, p53R282W) when combined with NSC 123127 (1 μM)
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Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 100 MG
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SB-408124 Hydrochloride is a selective, non-peptide orexin receptor 1 (OX1) antagonist. It demonstrates high potency with Ki values of 57 nM in whole cells and 27 nM in membranes, exhibiting 50-fold selectivity over the OX2 receptor. This compound is for research use only.
- Potent OX1 receptor antagonist (Ki: 57 nM in whole cells, 27 nM in membranes)
- Exhibits 50-fold selectivity over OX2 receptor
- Attenuates orexin A-induced AVP mRNA levels in neuronal cultures
- Reduces anxiety and restores corticoliberin levels in vivo
- Demonstrates an anxiolytic effect
- Reduces mean arterial pressure in salt-sensitive rats
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Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 25 MG
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Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of the TET enzyme. It is considered useful in the field of epigenetics and can serve as a starting point for new therapeutics targeting DNA methylation and gene transcription.
- Potent and selective inhibitor of TET enzyme
- IC50s of 33 μM for TET1 and 73 μM for TET2
- Significantly reduces global 5hmC levels in HT-22 cells
- Useful for epigenetics research
- Serves as a starting point for new therapeutics targeting DNA methylation and gene transcription
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Medchemexpress LLC Moexipril (hydrochloride) | 82586-52-5 | 1 ML
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Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE) that becomes effective after being hydrolyzed to moexiprila (hydrochloride). It demonstrates antihypertensive and neuroprotective effects and exhibits high potency against both plasma ACE and purified ACE from rabbit lung.
- Functions as an orally active ACE inhibitor
- Becomes effective after hydrolysis to moexiprila
- Demonstrates antihypertensive and neuroprotective effects
- High potency against plasma ACE and purified ACE from rabbit lung
- Reduces damaged neurons in a dose-dependent manner
- Attenuates Fe2+/3+-induced neurotoxicity
- Exhibits dose-dependent antihypertensive effects in various hypertensive rat and dog models
- Significantly reduces infarct area and cortical infarct volume in mouse and rat models of ischemic brain injury
- Supplied as a 10 mM solution in DMSO
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Medchemexpress LLC VU0453379 (hydrochloride) | 99.0% | 471.03 | 10 MG
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VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.
- Highly selective
- Central nervous system (CNS) penetrant
- Positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R)
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Medchemexpress LLC Mozavaptan (hydrochloride) | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 10MM 1ML
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Mozavaptan hydrochloride (OPC-31260) is the hydrochloride salt of a selective vasopressin V2 receptor antagonist. This product is supplied as a 10 mM solution in DMSO in a 1 mL vial for laboratory research use only.
- Ready-to-use 10 mM solution in DMSO.
- Supplied in a 1 mL sealed vial.
- High purity (99.9%).
- Molecular formula C27H30ClN3O2; molecular weight 464.0 g/mol.
- Recommended storage: 4°C sealed; in solvent: -80°C up to 6 months, -20°C up to 1 month.
- For research use only; not for human or diagnostic applications.
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5000382543 CP-547632 HYDROCHLO 25MG
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5000370841 TENOVIN-6 HYDROCHLO 50MG
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5000383548 CGS 21680 HYDROCHLO 10MM 1ML
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5000383630 AMSACRINE HYDROCHLO 10MM 1ML
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5000284970 LITTORINE HYDROCHLO 10MG
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