Sulfoxides
Medchemexpress LLC Cytochrome P450 3A4 Antibody (YA3715) | 10 UL
The CYP3A4 protein, a cytochrome P450 monooxygenase, is intricately involved in the metabolism of a diverse array of substrates, including sterols, steroid hormones, retinoids, and fatty acids. It plays a crucial role in various biological processes such as androgen and cholesterol metabolism, retinoid metabolism, and the oxidative metabolism of xenobiotics, acting as a major contributor to drug metabolism. This antibody also contributes to vitamin D catabolism and calcium homeostasis.
- Mouse-derived and non-conjugated IgG1 monoclonal antibody
- Targets Cytochrome P450 3A4
- Reactivity: Human, mouse, rat
- Formulated in PBS, pH 7.4
- Store at -20°C for 1 year
- Avoid repeated freeze / thaw cycles
- Liquid appearance
- Suitable for WB, IHC-P, ICC/IF, FC, ELISA applications
TARGETMOL CHEMICALS INC S1PR1 MODULATOR 1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6. purity: 99%
Medchemexpress LLC 3',4'-tetramethylene-α-pyrrolidinobutiophenone (hydrochloride) | 2749504-65-0 | 99.9% | 307.86 g/mol | C18H26ClNO | 10 MG
3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride is a synthetic research chemical classified as a drug derivative and intended for laboratory research use only. It is supplied as a white to off-white solid and is characterized by high purity according to manufacturer analytical data. Documentation such as a certificate of analysis and safety data sheet are provided.
Medchemexpress LLC Elafibranor sulfoxide | 95.0% | 400.49 | 25 MG
Elafibranor (GFT505) sulfoxide is a sulfoxide metabolite of Elafibranor (HY-16737). Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis.
- Purity: 95.0%
- Molecular weight: 400.49
- Formula: C22H24O5S
- Appearance: Solid
- Color: Light yellow to yellow
- Solubility (in vitro): 100 mg/mL (DMSO)
- Storage (powder): -20°C 3 years, 4°C 2 years
- Storage (in solvent): -80°C 6 months, -20°C 1 month
- Research use only
Medchemexpress LLC CB2R/FAAH modulator-2 | 2876918-68-0 | C₂₄H₃₃NO₂ | 5 MG
CB2R/FAAH modulator-2 | 2876918-68-0 | C₂₄H₃₃NO₂ | 5 MG
Medchemexpress LLC IL-17 modulator 3 | 2467731-88-8 | 99.5% | 579.73 | 1 MG
IL-17 modulator 3 is an IL-17 modulator, as described in US20200247785A1. It can be used for research related to inflammation, cancer, and autoimmune diseases. This compound is intended for research use only and is not sold to patients. It appears as a solid, with a color ranging from light yellow to yellow.
- Functions as an IL-17 modulator
- Useful for research related to inflammation, cancer, and autoimmune diseases
- Intended for research use only
- Appears as a solid
- Color ranges from light yellow to yellow
Medchemexpress LLC 3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride | 2749504-65-0 | 99.9% | 307.86 | 5 MG
This product is a laboratory chemical, 3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride, intended for research use only and suitable for the manufacture of substances. It should be handled by suitably qualified and experienced scientists in appropriately equipped and authorized facilities. The substance is stable under recommended storage conditions but is incompatible with strong acids/alkalis and strong oxidizing/reducing agents. It is not classified as a hazardous substance or mixture.
- Identified for laboratory use and substance manufacturing.
- Stable under recommended storage conditions.
- High purity of 99.9%.
- Molecular formula C18H26CINO.
- Powder storage: -20°C for 3 years, 4°C for 2 years.
- In solvent storage: -80°C for 6 months, -20°C for 1 month.
- Not a hazardous substance or mixture.
Medchemexpress LLC MicroRNA modulator-2 | 438599-31-6 | 432.49 | 5 MG
MicroRNA modulator-2 is an oxadiazole miR-21 inhibitor with AC50 of 16.48 μΜ.
- Target: MicroRNA
- Pathway: Epigenetics
Medchemexpress LLC mGluR3 modulator-1 | 374548-18-2 | MFCD01957075 | 98.7% | 271.36 g·mol⁻1 | C16H21N3O | 10 MG
mGluR3 modulator-1 is a small-molecule modulator of the metabotropic glutamate receptor 3 (mGluR3) intended for research use. It demonstrates activity in cellular calcium mobilization assays (EC50 = 1-10 μM) and is supplied with a reported high purity and defined molecular properties suitable for in vitro pharmacology and receptor profiling studies.
- Modulates mGluR3 receptor activity in cell-based assays.
- Demonstrated EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 calcium mobilization assay.
- High purity suitable for research applications.
- Available in small mass packages for screening and assay work.
- Includes chemical identifiers for traceability, such as CAS 374548-18-2.
Medchemexpress LLC Cytochrome P450 27A1 antibody (YA2163) | 100 UL
Cytochrome P450 27A1 Antibody (YA2163) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Cytochrome P450 27A1. This enzyme plays a crucial role in cholesterol homeostasis by catalyzing the hydroxylation of cholesterol and its derivatives, leading to bile acid synthesis and modulation of lipid metabolism genes.
- Rabbit-derived monoclonal antibody
- Targets Cytochrome P450 27A1
- Non-conjugated IgG
- Reactive with human, mouse, and rat samples
- Purified by affinity chromatography
- Predicted band size: 60 kDa; Observed band size: 50 kDa
- Suitable for WB, IHC-P, ICC/IF, and FC applications
