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AdipoGen Carboplatin
Chemical. CAS 41575-94-4. Formula C6H12N2O4Pt. MW 371.3. Potent platinum-based antineoplastic agent. Analog of cisplatin Prod. No. AG-CR1-3590 with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage.
