Cinnamic acids and derivatives
Apexbio Technology LLC trans-Cinnamic acid 140-10-3 20mg
trans-Cinnamic acid (140-10-3) is a small-molecule inhibitor that exerts inhibitory activity against specific enzyme targets involved in inflammation oxidative stress and microbial proliferation It modulates these biological processes thereby regulating pathways associated with inflammatory response and antimicrobial defense trans-Cinnamic acid exerts its biological activity primarily through enzyme inhibition In in vitro studies trans-Cinnamic acid demonstrates inhibitory activity with reported IC50 values typically between 50 200 M depending on the experimental conditions and cell models Based on these pharmacological properties trans-Cinnamic acid holds research potential in anti-inflammatory antimicrobial antioxidant response studies and metabolic assays in tissue culture and cell-based experimental models
![Medchemexpress LLC 2-propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 | C18H19NO3 | 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000209224.png-250.jpg)
Medchemexpress LLC 2-propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 | C18H19NO3 | 10 G
Aegeline is a high-purity natural alkaloid reference standard intended for analytical and pharmacological research. It is supplied as a solid and is also available as a DMSO solution for analytical use and method development.
- Purity 99.81%
- Cas number 456-12-2
- Molecular formula C18H19NO3
- Molecular weight 297.35 g/mol
- Physical form Solid and DMSO solution
- Typical applications Analytical standards, method development, and pharmacological research
- Available package sizes 500 mg, 1 g, 5 g, 10 g, and 50 g (quote)
- Product documents Data sheet and certificate of analysis available as PDF
![Medchemexpress LLC 2-Propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 g/mol | C18H19NO3 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000209428.png-250.jpg)
Medchemexpress LLC 2-Propenamide, N-[2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-, (2E)- | 456-12-2 | MFCD00048045 | 99.8% | 297.35 g/mol | C18H19NO3 | 1 G
Aegeline is an alkaloid reference standard intended for research use that mimics the yeast SNARE protein Sec22p and suppresses α-synuclein and Bax toxicity in yeast while exhibiting antioxidant activity.
- Alkaloid reference standard for research use.
- Cas number: 456-12-2.
- Chemical formula: C18H19NO3; molecular weight: 297.35 g/mol.
- Purity 99.81% (as provided on the certificate of analysis).
- Form: white to off-white solid powder.
- Solubility: soluble in DMSO (100 mg/mL); in vivo formulations listed for dosing preparations.
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solution at -80°C or -20°C for shorter periods.
- Pack size: 1 g.
Selleck Chemical LLC BLU 451-E1877-25MG
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Medchemexpress LLC HY-N7127 100mg Medchemexpress, (E)-m-Coumaric acid CAS:14755-02-3 Purity:>98%
Medchemexpress, HY-N7127 100mg (E)-m-Coumaric acid CAS:14755-02-3 (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Chem-Impex International, Inc. trans-Ferulic acid | 1135-24-6 | MFCD00004400 | 100G
trans-Ferulic acid, 1135-24-6, MFCD00004400, 100G
eMolecules 2'-(3-Fluorobenzyloxy)acetophenone | 845823-26-9 | MFCD06411645 | 1g
Oakwood Chemical | 2'-(3-Fluorobenzyloxy)acetophenone | 1g | 537680623 | 023221 | | 845823-26-9 | MFCD06411645 | 244.265 | C15H13FO2
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Apexbio Technology LLC Entacapone 130929-57-6 10mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Apexbio Technology LLC Entacapone sodium salt 1047659-02-8 100mg
Entacapone sodium salt (CAS 1047659-02-8) is a nitrocatechol small molecule that acts as a selective and reversible inhibitor of catechol-O-methyltransferase (COMT) a Mg2 -dependent enzyme involved in the metabolism of catecholamines and related compounds In biochemical assays entacapone exhibits an IC50 of 20 1 nM and a Ki of 10 7 nM for COMT inhibition The presence of a nitro group ortho to the hydroxyl group in its structure contributes to its inhibitory potency Entacapone has been widely used in research focused on Parkinson s disease particularly to study the modulation of levodopa bioavailability and pharmacokinetics