Coumarins and derivatives
Cayman Chemical Coumarin Boronic Acid pinacol
A fluorescent probe for detection of peroxynitrite; a more soluble form of CBA; can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide; COH displays ex/em = 332/470 nm, respectively
TARGETMOL CHEMICALS INC 7-ACETOXY-4-METHYLCOUMAR 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media a cell membrane environmental mimic to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin the fluorogenic substrate has been used to study the AchE inhibitor Tacrine·HCl (sc-200172). The compound has also been isolated from Trigonella foenum graceum. purity: 88%
Cayman Chemical 3-HydroxycoumarIn 5g
A coumarin with diverse biological activities; inhibits 15-LO-1 (IC50 = 9.5 µM); scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM); inhibits lipid peroxidation in vitro (IC50 = 69.07 mM); protective against UVB-induced embryotoxicity in sea urchins
Medchemexpress LLC My-1076 | 3008262-76-5 | MFCD35444266 | 99.1% | 539.57 g·mol-1 | C29H33NO9 | 10 MG
MY-1076 is a small-molecule inhibitor of Yes-associated protein (YAP) used for laboratory research. It induces YAP degradation and apoptosis and shows potent antiproliferative activity against several cancer cell lines with low-nanomolar IC50s. Reported properties include CAS 3008262-76-5, formula C29H33NO9, molecular weight 539.57 g·mol-1, and high reported purity.
- Induces YAP degradation and apoptosis in vitro
- Potent antiproliferative activity with low-nanomolar IC50s
- High purity suitable for analytical and biological studies
- Available in multiple small-scale quantities for research use
- Intended for research use only; not for human or clinical use
TARGETMOL CHEMICALS INC HX 531 10MG
Also available in 1 mg 5 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. HX 531 is a potent antagonist of the retinoid X receptor with an IC50 value of 18 nM. purity: 99%
Medchemexpress LLC Coumarin 480 | 41267-76-9 | MFCD00041844 | 100.0% | 255.31 g/mol | C16H17NO2 | 25 MG
Coumarin 480 (Coumarin 102) is a high-purity fluorescent laser dye used in fluorescence spectroscopy, laser applications, and optical research. It shows strong emission near 480 nm and is supplied as a research-grade reagent for imaging, sensor development, and photophysical studies. Users should follow the product SDS for safe handling and storage.
- High purity (99.95%).
- Strong fluorescence emission near 480 nm.
- Suitable for fluorescence spectroscopy and laser dye applications.
- Useful for sensor development and imaging studies.
- Provided as a research reagent in small vials.
Cayman Chemical 3-HydroxycoumarIn 1g
A coumarin with diverse biological activities; inhibits 15-LO-1 (IC50 = 9.5 µM); scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM); inhibits lipid peroxidation in vitro (IC50 = 69.07 mM); protective against UVB-induced embryotoxicity in sea urchins