Coumarins and derivatives
Cayman Chemical CoumarIn BoronIc AcId 50mg
A potent inhibitor of phosphatidic acid formation (IC50 0 6 UM) through cytokine-activated LPAAT suppresses the production of IFN-Y inhibits IL-12-mediated STAT-4 activation and enhances glucose-stimulatedBcell insulin secretion reduces the onset of diabetes in a non-obese diabetic mouse model
Selleck Chemical LLC 7-Methylcoumarin-E0656-100MG
7-Methylcoumarin can inhibit the growth of S aureus and the growth of Gram-positive bacteria within a concentration of 0 8 3 6 g/ml and also has a strong hepatoprotective activity
Indofine Chemical 7-Hydroxycoumarin, 99%, 250 Mg
Molecular Formula: C10H6O5, Purity >99%, Molecular Weight: 206.16, Melting Point >270C, Appearance: Cream colored powder, Solubility: Soluble in DMF, Storage conditions: Store in a cool, dry place, Also known as 3-Carboxy-7-hydroxycoumarin
Chem-Impex International, Inc. 7-Amino-4-methylcoumarin | 26093-31-2 | MFCD00006868 | 25G
7-Amino-4-methylcoumarin, 26093-31-2, MFCD00006868, 25G
Chem-Impex International, Inc. 7-Hydroxy-4-methylcoumarin | 90-33-5 | MFCD00006866 | 25G
7-Hydroxy-4-methylcoumarin, 90-33-5, MFCD00006866, 25G
Chem-Impex International, Inc. Esculin hydrate | 531-75-9 | MFCD00149492 | 25G
Esculin hydrate, 531-75-9, MFCD00149492, 25G
Cayman Chemical 7-EthoxycoumarIn 1g
An EZH2 inhibitor (IC50 11 1 nM) colony formation of primary human CD34 CML stem/progenitor cells at 0 5-5 UM reduces global levels of H3K27me3 in K562 cells induces regression of tumors in an EZH2-driven transgenic mouse model of lung adenocarcinoma at 75 mg/kg per day
Cayman Chemical 7-EthoxycoumarIn 500mg
An a-pyrone fungal metabolite with antifungal activity active against C neoformans A fumigatus A niger and A flavus human mycoses (MICs 1 56-6 25 g/ml) active against a variety of filamentous fungi in a disc assay
Sigma Organic Chemistry Umbelliferone | 25G | 93-35-6 | MFCD00006878
Umbelliferone, 25G
About This Item:
Storage: room temp
EINECS Number: 202-240-3
Sigma Organic Chemistry 3-Aminocoumarin | 1G | 1635-31-0 | MFCD00016965
3-Aminocoumarin , 1G
About this item:
CAS #: 1635-31-0
MDL #: MFCD00016965
Purity: ≥97
Molecular Weight: 161.16
UNSPSC Code: 12352100
Sigma Organic Chemistry Coumarin 6 | 5G | 38215-36-0 | MFCD00041869 | 0.98
Coumarin 6, 5G
About This Item:
Storage: room temp
EINECS Number: 253-830-2
Apexbio Technology LLC 6,7-Dihydroxycoumarin 305-01-1 20mg
6 7-Dihydroxycoumarin (CAS 305-01-1) also known as esculetin is a naturally occurring coumarin derivative extracted from Aesculus hippocastanum Linn This compound exhibits notable antioxidant activity primarily by scavenging reactive oxygen species and inhibiting lipid peroxidation Additionally 6 7-dihydroxycoumarin has been studied for its modulatory effects on various cellular signaling pathways implicated in inflammation and apoptosis Its applications in biomedical research include investigations into oxidative stress inflammation and related disease models The compound is soluble in ethanol and dilute alkali and should be stored in a sealed cool and dry environment to preserve stability
Sigma Organic Chemistry 4-Bromomethyl-7-methoxycoumarin | 5G | 35231-44-8 | MFCD00006869
CAS #: 35231-44-8
MDL #: MFCD00006869
Purity: >97 %
UNSPSC Code: 12352100
Molecular Weight: 269.09
Sigma Organic Chemistry 3-(Ethylamino)-p-cresol | 5G | 120-37-6 | MFCD00002382
CAS #: 120-37-6
MDL #: MFCD00002382
Purity: >90%
UNSPSC Code: 12352100
Molecular Weight: 151.21
Apexbio Technology LLC 7-Amino-4-(trifluoromethyl)coumarin 53518-15-3 100mg
7-Amino-4-trifluoromethyl coumarin (CAS 53518-15-3) is a small-molecule antagonist targeting serotonin receptor subtype 1E (HTR1E) galanin receptor 2 (GALR2) and gamma receptor subtype 2 (GalR2) It is designed to antagonize these receptors thereby modulating receptor-mediated signaling pathways 7-Amino-4-trifluoromethyl coumarin exerts its biological activity primarily through receptor antagonism and inhibition of hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4) enzymatic activity In biochemical assays it demonstrates inhibitory activity toward HSD17B4 with reported bioactivity at approximately 21 M Based on these pharmacological properties 7-Amino-4-trifluoromethyl coumarin holds research potential in the investigation of protease activity receptor-mediated signaling and metabolic enzyme regulation