Dihydrocoumarins
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Medchemexpress LLC Dihydrocoumarin | 119-84-6 | 148.16 | 1 ML
Dihydrocoumarin is a compound found in *Melilotus officinalis*. It acts as a yeast Sir2p inhibitor and also inhibits human SIRT1 and SIRT2. This compound induces concentration-dependent inhibition in enzymatic assays, and increases cytotoxicity, apoptosis, and p53 lysine acetylation in the TK6 cell line.
- Yeast Sir2p inhibitor
- Inhibits human SIRT1 and SIRT2
- Increases cytotoxicity and apoptosis in TK6 cell line
- Increases p53 lysine acetylation in TK6 cell line
