Linear 1 3-diarylpropanoids
Apexbio Technology LLC Phloretin 60-82-2 10mM (in 1mL DMSO)
Phloretin (CAS 60-82-2) is a naturally occurring dihydrochalcone phenolic compound derived primarily from apple leaves and Manchurian apricot It functions as an inhibitor of sodium-glucose linked transporters (SGLT1 and SGLT2) proteins involved in glucose uptake and reabsorption in intestinal and renal tissues Phloretin inhibits glucose uptake via these transporters exhibiting an IC50 of approximately 49 12 M In cell-based studies it enhances lipolysis increases AMP-activated protein kinase (AMPK) phosphorylation and suppresses adipogenic transcription factors and MAPK signaling Animal research demonstrates that oral administration of Phloretin reduces blood glucose and improves lipid profiles in diabetic mouse models highlighting its utility in metabolic research
Selleck Chemical LLC 4-Hydroxychalcone S4937-100mg
4 -Hydroxychalcone (P-Cinnamoylphenol) found in herbs and spices and tea is a member of the class of compounds known as retrochalcones It has diverse biological activities inhibiting TNF -induced NF- B pathway activation in a dose-dependent manner and activating BMP signaling
Sigma Aldrich Fine Chemicals Biosciences Xanthohumol from hop Humul5MG
Xanthohumol is a chalcone compound present in the female inflorescence of hop (Humulus lupulus) plant. It is a food additive.
