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Linear 1 3-diarylpropanoids

Organic compounds contain a central propyl group (3 carbon chain) with one phenyl group bonded to the first and the third carbons in the propyl chain; the propyl chain may contain other functional groups, such as a carbon - carbon double bond.

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Medchemexpress LLC 4'-Hydroxychalcone | 2657-25-2 | 1 ML
SDP

4'-Hydroxychalcone is a chalcone isolated from licorice root with hepatoprotective activity. It inhibits TNFa-induced NF-κB activation via proteasome inhibition. It also induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria.

  • Isolated from licorice root
  • Exhibits hepatoprotective activity
  • Inhibits TNFa-induced NF-κB activation through proteasome inhibition
  • Induces rapid potassium release from mitochondrial vesicles
  • Causes deterioration of respiratory control and oxidative phosphorylation
  • Affects cancer cell viability

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