Macrolide lactams
Tacrolimus Monohydrate 80.0+%, TCI America™
CAS: 109581-93-3 Molecular Formula: C44H71NO13 Molecular Weight (g/mol): 822.046 MDL Number: MFCD11045918 InChI Key: NWJQLQGQZSIBAF-MLAUYUEBSA-N Synonym: FK 506 PubChem CID: 5282315 ChEBI: CHEBI:61057 SMILES: CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC.O
Medchemexpress LLC LL-37 FK-13 (TFA) | 98.6% | 1719.09 | 10 MG
LL-37 FK-13 TFA is the TFA salt form of LL-37 FK-13. It functions as an antimicrobial agent that inhibits *Trichomonas vaginalis*. This compound demonstrates minimal hemolytic effects on human erythrocytes and low cytotoxicity to human fibroblasts.
- TFA salt form of LL-37 FK-13
- Functions as an antimicrobial agent
- Inhibits *Trichomonas vaginalis*
- Demonstrates minimal hemolytic effects on human erythrocytes
- Exhibits low cytotoxicity to human fibroblasts
- Appears as a solid, white to off-white in color
- Soluble in H2O at ≥ 100 mg/mL
AdipoGen FK-506 Tacrolimus
Chemical. CAS 109581-93-3. Formula C44H69NO12 . H2O. MW 804.0 . 18.0. Isolated from Streptomyces FCZ0311. Potent immunosuppressant as cyclosporin A and rapamycin. Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 IL-2. Forms a complex with FK-506 binding protein 12 FKBP12. Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B PP2B calcineurin, leading to disruption of T cell activation. Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases e.g. atopic dermatitis and with potential anti-rheumatic activity rheumatoid arthritis. Neuroprotective. Regulates nitric oxide neurotoxicity. Neurotransmitter. Ca2 release compound. NF-kappaB suppressor by induction of unfolded protein response UPR. Anti-cancer compound. Apoptosis inducer.