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Organic compounds characterized by having a lactone ring (14–16 atoms) bonded to one or more deoxy sugar molecules; they are a class of closely related antibiotics. Analogues (compounds with similar structure) are included.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More