Phenols
Apexbio Technology LLC Valnemulin HCl 133868-46-9 10mM (in 1mL DMSO)
Valnemulin HCl (CAS 133868-46-9) is a small-molecule inhibitor targeting bacterial protein synthesis It is designed to inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit thereby disrupting peptide bond formation and bacterial growth Valnemulin HCl exerts its biological activity primarily through specific binding to the peptidyl transferase region within the 50S ribosomal subunit In experimental animal models valnemulin HCl demonstrates inhibitory effects on Mycoplasma bovis proliferation in calf lung tissues with reported IC50 values against various bacterial isolates ranging from approximately 0 03 to 0 5 g/mL depending on the bacterial strain Based on these pharmacological properties valnemulin HCl holds research potential in the management of bacterial infections including applications in epizootic rabbit enteropathy and respiratory diseases in livestock
