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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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Enclomiphene citrate (CAS 7599-79-3) is a small-molecule antagonist targeting estrogen receptors It is designed to competitively bind to estrogen receptors thereby inhibiting receptor-mediated estrogen signaling and attenuating estrogen-induced negative feedback on the hypothalamic-pituitary axis Enclomiphene citrate exerts its biological activity primarily by increasing endogenous secretion of gonadotropins including luteinizing hormone (LH) and follicle stimulating hormone (FSH) which promotes endogenous testosterone biosynthesis in gonadal tissues Based on these pharmacological properties enclomiphene citrate holds research potential in studies of male hypogonadism fertility disorders and regulation of male gonadal function
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Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that works by acting as an H K and Pb2 ionophore Nigericin can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes
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