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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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(R)-(-)-Gossypol (AT-101) acetic acid the R-(-) enantiomer of Gossypol acetic acid binds with Bcl-2 Bcl-xL and Mcl-1 with Ki of 0 32 M 0 48 M and 0 18 M in cell-free assays does not inhibit BIR3 domain and BID AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy Phase 2
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MG-101 (ALLN Calpain inhibitor-1 Ac-LLnL-CHO) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins
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BODIPY FL hydrazide is a green-fluorescent hydrazide reagent that reacts with aldehyde and ketone groups on polysaccharides and glycoproteins to form a reversible Schiff base that can be reduced to a stable linkage for detection and imaging. Its excitation maximum is about 495 nm and its emission maximum is about 516 nm.
Reactive toward aldehyde and ketone groups
Forms a reversible Schiff base convertible to a stable linkage by reduction
Green fluorescence with excitation ~495 nm and emission ~516 nm
Suitable for fluorescent labeling of carbohydrates and glycoproteins
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Phenylbutazone(diphenyl-d10) is the deuterium labeled Phenylbutazone. It functions as an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS) and is also known as a hepatotoxin and a nonsteroidal anti-inflammatory agent (NSAID). This compound induces muscle blind-like protein 1 (MBNL1) expression and has potential applications in ankylosing spondylitis research.
Acts as an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS)
Functions as a hepatotoxin and a nonsteroidal anti-inflammatory agent (NSAID)
Induces muscle blind-like protein 1 (MBNL1) expression
Has potential for ankylosing spondylitis research
Can be used as a tracer in various studies
Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Biotin-XX hydrazide is a carbonyl-reactive biotinylation reagent that contains two aminohexanoic acid spacers to improve avidin-binding efficiency. It couples to carbonyl groups on biomolecules to produce biotinylated targets suitable for detection, enrichment, and affinity capture using streptavidin or avidin methods.
Contains two aminohexanoic acid spacers to enhance binding efficiency.
Reacts selectively with carbonyl groups for targeted labeling.
Enables affinity capture and detection with streptavidin or avidin systems.
Supplied as a 5 mg package suitable for laboratory-scale experiments.
High purity as determined by RP-HPLC for reliable results.
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