Carboxylic acids and derivatives
Medchemexpress LLC Arl67156 trisodium | 1021868-83-6 | 99.9% | 785.05 g·mol-1 | C15H21Br2N5Na3O12P3 | 1 MG
ARL67156 trisodium is a small-molecule research inhibitor of ecto-ATPase (NTPDase) enzymes, provided as the trisodium salt in solid form. It is used to study nucleotide hydrolysis and related pathologies such as calcific aortic valve disease and asthma.
- Selective inhibitor of NTPDase1 (CD39), NTPDase3, and NPP1.
- Reported Ki values approximately 11 μM (NTPDase1), 18 μM (NTPDase3), and 12 μM (NPP1).
- High reported purity (99.94%).
- Molecular weight about 785.05 g·mol-1 and exact formula C15H21Br2N5Na3O12P3.
- Supplied as a solid trisodium salt, available in small research pack sizes.
- Store sealed and away from moisture at -20°C; in solution, store at -80°C (up to 6 months) or -20°C (up to 1 month).
Medchemexpress LLC DiMal-O-CH2COOH | 1620837-47-9 | 96.81% | C13H12N2O7 | 100 MG
diMal-O-CH2COOH is a cleavable ADC linker. It is for research use only and not intended for human use. This product appears as a solid with a white to off-white color.
- Cleavable ADC linker
- For research use only
- Not intended for human use
- Appears as a solid
- Color: white to off-white
- Molecular weight: 308.24
Chem Service Inc Triethyl citrate | 77-93-0 | MFCD00009201 | 1g
This item has a minimum order quantity of 3 per supplier requirements
Triethyl citrate | Putity: 99.5 | MW: 276.29 | 77-93-0 | MFCD00009201 | 1g
Medchemexpress LLC Magnesium citrate 100mg
Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2]
Chem-Impex International, Inc. (-)-Tri-O-acetyl-D-glucal | MFCD00063253 | 25G
(-)-Tri-O-acetyl-D-glucal, MFCD00063253, 25G
Apexbio Technology LLC Toremifene Citrate 89778-27-8 10mM (in 1mL DMSO)
Toremifene Citrate (CAS 89778-27-8) is a small-molecule selective estrogen receptor modulator (SERM) targeting estrogen receptors It is designed to modulate estrogen receptor signaling pathways thereby regulating estrogen-dependent cellular functions Toremifene Citrate exerts its biological activity primarily through tissue-specific antagonism or partial agonism of the estrogen receptor In in vitro studies Toremifene Citrate demonstrates receptor binding activity with an affinity of 1 M for the estrogen receptor Based on these pharmacological properties Toremifene Citrate holds research potential in investigating estrogen-dependent regulatory processes and endocrine signaling dynamics
Medchemexpress LLC Iacs-8803 diammonium | 00-00-0 | 98.8% | 726.60 g/mol | C20H29FN12O9P2S2 | 5 MG
IACS-8803 diammonium is a potent cyclic dinucleotide STING agonist for preclinical research that activates the STING pathway and has demonstrated systemic antitumor efficacy. The diammonium salt form improves stability for handling and experimental use and is supplied with supporting analytical and safety documentation for research workflows.
- High purity suitable for research use (98.8%).
- Potent STING agonist activity for immuno-oncology studies.
- Suitable for both in vitro and in vivo preclinical experiments.
- Provided with SDS, COA, HNMR, LCMS, and analytical reports.
- Available in multiple small research pack sizes for dose-ranging studies.
Medchemexpress LLC Citrate synthase | 9027-96-7 | ~98 KDa dimer (49 KDa monomer) | 500 U
Citrate synthase catalyzes the initial reaction of the citric acid cycle, condensing acetyl-CoA and oxaloacetate to form citrate. This enzyme is primarily localized within the mitochondrial matrix of eukaryotic cells. Each unit of the enzyme is defined by its ability to form 1.0 μmole of citrate from oxalacetate and acetyl CoA per minute at pH 8.0 at 37°C.
- Catalyzes key reaction in citric acid cycle
- Localized in mitochondrial matrix
- Biochemical reagent
- Metabolic enzyme/protease
- Endogenous metabolite
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 3768-14-7 | 99.9% | 476.32 | 10 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor, and it can be utilized for research into the ATP-adenosine pathway.
- Functions as a CD73 inhibitor.
- Useful for research concerning the ATP-adenosine pathway.
- Inhibits 5'-AMP induced adenosine formation in A498 cells at concentrations of 20 and 100 μmol/L.
Selleck Chemical LLC D-()-Galacturonic acid monohydrate S3310-25mg
D-( )-Galacturonic acid monohydrate (D-Galacturonic acid hydrate d-GalA D-galUA) is an endogenous metabolite that can be used in engineering Saccharomyces cerevisiae
Selleck Chemical LLC Ixazomib Citrate (MLN9708) Analogue S2181-10mM/1mL
Ixazomib Citrate (MLN9708) Analogue is the analogue of Ixazomib Citrate (MLN9708) from WO2016165677A1 Ixazomib Citrate (MLN9708) immediately hydrolyzed to Ixazomib (MLN2238) the biologically active form on exposure to aqueous solutions or plasma Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic ( 5) site of the 20S proteasome with IC50/Ki of 3 4 nM/0 93 nM in cell-free assays less potent to 1 and little activity to 2 Ixazomib (MLN2238) induces autophagy Phase 3
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.2% | 10 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound also functions as a PEG-based PROTAC linker for the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Used in the synthesis of antibody-drug conjugates
- Used in the synthesis of PROTACs
- Molecular formula: C29H39NO10
- Molecular weight: 561.62
- Soluble in DMSO at 100 mg/mL (178.06 mM); requires ultrasonic
Medchemexpress LLC ζ-Stat trisodium | 31894-34-5 | 97.0% | 450.31 g/mol | C10H5Na3O10S3 | 5MG
ζ-Stat trisodium (trisodium;8-hydroxynaphthalene-1,3,6-trisulfonate) is the trisodium salt of NSC37044 and a selective inhibitor of atypical protein kinase C zeta (PKC-ζ). It is provided as a light yellow to light brown solid for biochemical and cellular research and has been reported to reduce melanoma cell proliferation and induce apoptosis in vitro.