Azoles
Apexbio Technology LLC YL-109 36341-25-0 10mM (in 1mL DMSO)
YL-109 (CAS 36341-25-0) is a small molecule with demonstrated antitumor properties primarily acting through modulation of the aryl hydrocarbon receptor (AhR) signaling pathway This compound enhances expression of the molecular chaperone-associated ubiquitin ligase CHIP (C-terminus of Hsp70-interacting protein) leading to downstream regulation of processes implicated in cell proliferation and invasion In breast cancer models YL-109 induces CHIP expression resulting in suppressed proliferation and invasive capabilities of cancer cells YL-109 is thus a valuable tool for investigating AhR-mediated anticancer mechanisms and exploring therapeutic strategies in breast cancer research
Medchemexpress LLC Atopaxar | 751475-53-3 | 99.9% | 527.63 | 5 MG
Atopaxar is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. As an antiplatelet agent, it interferes with platelet signaling and can be used for the research of atherothrombotic disease.
- Potent, orally active, selective and reversible PAR-1 antagonist
- Interferes with platelet signaling
- Used for research of atherothrombotic disease
- Inhibits human platelet aggregation induced by thrombin or TRAP
- Does not inhibit PRP aggregation induced by ADP, U46619, collagen, and PAR-4ap, up to 20 μM
- Causes dose-dependent prolongation of time to occlusion of the femoral artery in photochemically-induced thrombosis (PIT) guinea pigs model
- Does not prolong bleeding time in guinea pigs at high dosages
![Medchemexpress LLC (S)-4-(8-Amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl-d4)benzamide | 2699608-18-7 | >=98.0% | 469.53 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387530-logo.png-250.jpg){kind=logo}
Medchemexpress LLC (S)-4-(8-Amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl-d4)benzamide | 2699608-18-7 | >=98.0% | 469.53 | 1 MG
Acalabrutinib-d4 (ACP-196-d4) is a deuterium labeled Acalabrutinib, an orally active, irreversible, and highly selective second-generation BTK inhibitor. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Used as a tracer for quantitation during drug development.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes to affect pharmacokinetic and metabolic profiles.
- Suitable for research use only.
Sigma Aldrich Fine Chemicals Biosciences Candesartan cilexetil Related Compound D United States Pharmacopeia (USP) Reference Standard | 1185256-03-4 | 10MG
Candesartan cilexetil Related Compound D United States Pharmacopeia (USP) Reference Standard | Mol Wt: 610.66 | 1185256-03-4 | 10MG
Medchemexpress LLC (2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid | 1012341-52-4 | 99.0% | C23H29NO4 | 50 MG
(2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid is a drug intermediate for the synthesis of various active compounds. It is intended for research use only and not for sale to patients.
- Drug intermediate for synthesis of various active compounds
- For research use only
- Appears as a solid
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC HY-100018 2mg Medchemexpress, BAY1125976 CAS:1402608-02-9 Purity:>98%
Medchemexpress, HY-100018 2mg BAY1125976 CAS:1402608-02-9 BAY1125976 is a selective allosteric Akt1/Akt2 inhibitor; inhibits Akt1 and Akt2 activity with IC 50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone | 141645-16-1 | 99.6% | C19H17NO5 | 10 G
(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone is a drug intermediate for the synthesis of various active compounds.
- Used for synthesis of various active compounds.
- For research use only.
eMolecules Ethyl 4-amino-1h-pyrazole-5-carboxylate | 55904-61-5 | MFCD06739331 | 1g
Combi-Blocks | Ethyl 4-amino-1h-pyrazole-5-carboxylate | 1g | 448003360 | QH-0758 | 97.000 | 55904-61-5 | MFCD06739331 | 155.157 | C6H9N3O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool