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Label live cell surface glycoproteins with visible red fluorescent dye (Ex/Em 550/570 nm) for fixable plasma membrane staining GlycoLiner uses novel reactive chemistry for faster more efficient and gentler labeling compared to conventional methods 500 reactions for imaging (100 uL volume)
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YL-939 is a potent ferroptosis inhibitor that targets the PHB2/ferritin/iron axis. It efficiently protects cells from ferroptosis with IC50 values ranging from 0.14 μM to 0.25 μM for various cell lines. It also reduces the level of reactive oxygen species (ROS) in cytosolic and membrane lipids.
Ameliorates liver damage in an acetaminophen-induced acute liver injury mouse model.
Inhibits cell death and inflammatory infiltration in liver tissues.
Improves ferritin protein expression in a concentration-dependent manner.