Anticancer agent 93 is a 4-Hydroxycoumarin derivative that demonstrates efficacy against lung cancer cells. It inhibits invasion and migration by modulating epithelial-mesenchymal transition (EMT) effectors, making it a potential candidate for cancer research.
- Inhibits A549 cell invasion by approximately 50%
- Significantly inhibits A549 cell migration
- Decreases lung cancer cell motility by downregulating EMT markers
- Reduces expression of N-cadherin and E-cadherin in A549 cells