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Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
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Invertase, baker's yeast (S. cerevisiae) is a significant enzyme found in plants and microorganisms, frequently utilized in biochemical studies. It catalyzes the hydrolysis of the disaccharide sucrose into glucose and fructose. This product is derived from deep microbial fermentation and is employed to catalyze sucrose hydrolysis.
Optimal temperature range: The effective temperature range is 20-60°C, with an optimal temperature between 45-55°C.
Optimal pH range: The effective pH range is 3.0-8.0, with an optimal pH of 4.5-5.5.
Inhibitors: Inhibited by Fe3+, Cu2+, Hg+, and Pb+.
Solubility: Soluble in water (≥ 100 mg/mL).
Storage and handling: Avoid repeated freezing and thawing. Store at 2-8°C and use within one week.
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Sec61-IN-1 (compound A317) is a small-molecule inhibitor of the Sec61 translocon developed for research use. It selectively inhibits Sec61-mediated protein translocation, shows cytotoxic activity in certain glioma models, and can enhance T cell-mediated cytotoxicity in vitro; it also shows measurable brain exposure in mouse studies. Supplied as a solid or as a DMSO solution for laboratory studies.
Potent Sec61 inhibition in vitro.
Enhances T cell-mediated cytotoxicity against glioma cells.
Demonstrated activity in SEC61G-EGFR amplified glioblastoma models.
Detectable brain exposure after intravenous dosing in mice.
Available as solid and as a DMSO solution for formulation flexibility.
High purity suitable for research (99.7%).
Recommended storage conditions provided to preserve stability.
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Potassium (bromomethyl)trifluoroborate is an organotrifluoroborate reagent supplied as the potassium salt and commonly used in organic synthesis as a stable, crystalline building block for cross-coupling and functionalization reactions. It is handled as a solid reagent for laboratory research and is typically stored cool and dry.
Organoboron reagent for cross-coupling reactions.
Stable potassium trifluoroborate salt in solid form.
Useful as a bromomethyl transfer building block in synthesis.
Suitable for medicinal chemistry and method development.
Typical appearance: white to almost white powder or crystals.
Store in a cool, dry place to maintain stability.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
YTX-465 is a small-molecule stearoyl-CoA desaturase inhibitor used in research applications, including studies of Parkinson's disease and other synucleinopathies. It is supplied as a white to off-white solid intended for in vitro research and biochemical assays, and demonstrates potent activity against the Ole1 target.
Inhibits Ole1 and SCD1 with IC50 values of 0.039 μM and 30.4 μM respectively.
Molecular weight 458.51 and formula C25H26N6O3.
High purity (≈99.1%) based on supplier assay results.
White to off-white solid suitable for formulation in DMSO.
Recommended storage: 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
Available in multiple small pack sizes and as a 10 mM solution in DMSO for convenience.
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