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Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
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N-Methylindan-2-amine hydrochloride (compound 3b) is an N-alkylated congener of phenylethylamine that increases hot plate reaction time in mice without inducing dopaminergic effects. It can be used to study central noradrenergic mechanisms. This product is for research use only and not sold to patients.
Used to study central noradrenergic mechanisms
Increases hot plate reaction time in mice
Does not induce dopaminergic effects
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Medchemexpress, HY-17364 50mg Temozolomide CAS:85622-93-1 Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Mizolastine (CAS 108612-45-9) is a selective antagonist of the histamine H1 receptor exhibiting an inhibitory concentration (IC50) of 47 nM By blocking H1 receptor-mediated signaling Mizolastine effectively attenuates histamine-induced cellular responses involved in allergic inflammation This compound is utilized in biomedical research to investigate mechanisms underlying allergic disorders such as seasonal allergic rhinitis and urticaria and to evaluate therapeutic strategies targeting H1 receptor pathways in allergic and inflammatory conditions
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GAL-02-221 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. It can potently degrade BRD4 in HER2 positive and negative breast cancer cell lines.
Potently degrades BRD4
Degrades BRD4 in HER2 positive and negative breast cancer cell lines
Connected by ligands for von Hippel-Lindau and BRD4
Shows antiproliferative activity against human 22Rv1, L02, MCF7, and MDA-MB-231 cells
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