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Azoles

Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
Imidazoles (2,980)
Thiazoles (2,030)
Pyrazoles (1,492)
Triazoles (581)
Oxazoles (557)
Oxadiazoles (242)
Isoxazoles (232)
Thiadiazoles (71)
Dithiazoles (4)

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3,286 – 3,300 of 6,965 results
3,286

Medchemexpress LLC Phospho-CDK1/2/3 (Thr14) Antibody (YA218) | 50 UL
SDP

Phospho-CDK1/2/3 (Thr14) Antibody (YA218) is a Rabbit-derived, non-conjugated IgG monoclonal antibody, specifically targeting the phosphorylated Thr14 site of CDK1, CDK2, and CDK3. These cyclin-dependent kinases are pivotal regulators of the eukaryotic cell cycle, controlling G0-G1, G1-S, and G2-M transitions, DNA synthesis, and cell proliferation. This antibody supports cell biology research into the regulatory mechanisms and subcellular localization of these essential kinases.

  • Rabbit-derived monoclonal antibody
  • Targets phosphorylated Thr14 of CDK1, CDK2, and CDK3
  • Essential for studying cell cycle regulation
  • Aids research into DNA synthesis and cell proliferation
  • Non-conjugated IgG isotype
  • Suitable for Western Blot (WB) and Immunoprecipitation (IP) applications
  • Predicted and observed molecular weight: 34 kDa
  • Affinity purified for high specificity
  • Stable for 1 year when stored at -20°C

ENCOMPASS_PREFERRED
3,287

Medchemexpress LLC Isobutyl-deoxynyboquinone | 1430798-22-3 | 99.7% | 326.35 | C18H18N2O4 | 5MG
SDP

Isobutyl-deoxynyboquinone (IB-DNQ) is a small-molecule quinone used as a selective substrate for NAD(P)H:quinone oxidoreductase 1 (NQO1) in preclinical research. It is employed to probe NQO1-dependent cytotoxicity and has demonstrated in vitro potency across cancer cell lines, with documented in vivo exposure in pharmacokinetic studies.

  • Selective substrate for NQO1.
  • Used to study NQO1-mediated cytotoxicity in cell-based assays.
  • Demonstrates in vitro activity in SCCF cell lines.
  • Molecular formula C18H18N2O4; molecular weight 326.35.
  • Purity 99.7%.
  • Appearance brown to red solid.
  • Solubility DMSO 10 mg/mL; may require warming or sonication.
  • Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years); stock solutions: -80°C (6 months).

ENCOMPASS_PREFERRED
3,288

Medchemexpress LLC YL-5092 | 3056857-07-6 | 99.8% | 441.43 | 1 ML
SDP

YL-5092 is a selective YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) inhibitor with an IC50 of 7.4 nM and a KD of 29.6 nM. It can suppress cancer cell proliferation and induce cell G0/G1 phase arrest and apoptosis. YL-5092 is used for cancer research, including acute myeloid leukemia (AML).

  • Selectively inhibits YT521-B homology (YTH) domain-containing protein 1.
  • Suppresses cancer cell proliferation.
  • Induces cell G0/G1 phase arrest.
  • Promotes apoptosis in cancer cells.
  • Impairs leukemogenesis and improves survival rates in mouse tumor models.
  • Reduces leukemia infiltration in peripheral blood, spleen, and bone marrow.
  • Decreases the expression of YTHDC1 target genes like MYC, FOXM1, GINS1, MCM2, MCM4, and MCM5.

ENCOMPASS_PREFERRED
3,289

eMolecules​ AstaTech / 2-(26-DICHLORO-4-PYRIDYL)-2-PROPANOL / 0.25g / 437209719 / 31728 / 97.000 / 95037-35-7 / MFCD18375241 / 206.070 / C8H9Cl2NO

AstaTech / 2-(26-DICHLORO-4-PYRIDYL)-2-PROPANOL / 0.25g / 437209719 / 31728 / 97.000 / 95037-35-7 / MFCD18375241 / 206.070 / C8H9Cl2NO

ENCOMPASS_PREFERRED
3,290

Medchemexpress LLC FAM49B 190-198 mou | 5MG
SDP

FAM49B 190-198 mou | 5MG

ENCOMPASS_PREFERRED
3,291

eMolecules​ EMOLECULES INC

5000190841 1H-IMIDAZOLE-1-SULFONYL 250MG

ENCOMPASS_PREFERRED
3,292

Medchemexpress LLC ENDO S2 S. PYOGENES 10UG
SDP

5000194766 ENDO S2 S. PYOGENES 10UG

ENCOMPASS_PREFERRED
3,293

Sigma Aldrich Fine Chemicals Biosciences Thiazolyl Blue Tetrazolium Bromide | 298-93-1 | MFCD00011964 | 500mg

Thiazolyl Blue Tetrazolium Bromide | Purity: 97.5% | Mol Wt: 414.32 | 298-93-1 | MFCD00011964 | 500mg

ENCOMPASS
3,294

eMolecules​ Medchem Express / Galicaftor / 5mg / 719836524 / HY-111111 / / 1918143-53-9 / [null] / 559.470 / C28H21F4NO7

Medchem Express / Galicaftor / 5mg / 719836524 / HY-111111 / / 1918143-53-9 / [null] / 559.470 / C28H21F4NO7

ENCOMPASS_PREFERRED
3,295

Selleck Chemical LLC BAY 1436032
SDP

BAY-1436032 is a highly selective potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants

ENCOMPASS_PREFERRED
3,296

eMolecules​ Medchem Express / Terevalefim / 5mg / 665626281 / HY-137455 / / 1070881-42-3 / [null] / 176.240 / C9H8N2S

Medchem Express / Terevalefim / 5mg / 665626281 / HY-137455 / / 1070881-42-3 / [null] / 176.240 / C9H8N2S

ENCOMPASS_PREFERRED
3,297

Accela Chembio Inc 1-hexyl-3-methylimidazolium Tetrafluoroborate | 100g | 244193-50-8 | MFCD03095459 | 97+% | D: 1.149 | Shelf Life: 1440 Days | Moisture Sensitive/n2
SDP

1-hexyl-3-methylimidazolium Tetrafluoroborate | 100g | 244193-50-8 | MFCD03095459 | 97+% | D: 1.149 | Shelf Life: 1440 Days | Moisture Sensitive/n2

ENCOMPASS_PREFERRED
3,298

Medchemexpress LLC cGAMP disodium | 2407516-83-8 | 98.5% | 718.37 | 10 MM * 1 ML
SDP

cGAMP disodium | 2407516-83-8 | 98.5% | 718.37 | 10 MM * 1 ML

ENCOMPASS_PREFERRED
3,299

Sigma Aldrich Fine Chemicals Biosciences Azilsartan >=98% (HPLC) | 147403-03-0 | MFCD00916395 | 10MG

Azilsartan >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 456.45 | 147403-03-0 | MFCD00916395 | 10MG

ENCOMPASS
3,300

Sigma Aldrich Fine Chemicals Biosciences Candesartan cilexetil >=98% (HPLC) | 145040-37-5 | MFCD00871371 | 50MG

Candesartan cilexetil >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 610.66 | 145040-37-5 | MFCD00871371 | 50MG

ENCOMPASS